WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2006088988) CRYSTALLINE FORM OF AN INDAZOLE-CARBOXAMIDE COMPOUND
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/088988    International Application No.:    PCT/US2006/005399
Publication Date: 24.08.2006 International Filing Date: 16.02.2006
IPC:
C07D 451/04 (2006.01), A61K 31/46 (2006.01)
Applicants: THERAVANCE, INC. [US/US]; 901 Gateway Boulevard, South San Francisco, CA 94080 (US) (For All Designated States Except US).
FATHEREE, Paul, R. [US/US]; (US) (For US Only).
TURNER, Derek, S. [US/US]; (US) (For US Only).
CHAO, Robert [US/US]; (US) (For US Only).
LIU, Jyanwei [US/US]; (US) (For US Only).
ZHANG, Hao [US/US]; (US) (For US Only).
GENOV, Daniel [US/US]; (US) (For US Only).
LEE, Junning [US/US]; (US) (For US Only)
Inventors: FATHEREE, Paul, R.; (US).
TURNER, Derek, S.; (US).
CHAO, Robert; (US).
LIU, Jyanwei; (US).
ZHANG, Hao; (US).
GENOV, Daniel; (US).
LEE, Junning; (US)
Agent: HAGENAH, Jeffrey, A.; Theravance, Inc., 901 Gateway Boulevard, South San Francisco, CA 94080 (US)
Priority Data:
60/653,677 17.02.2005 US
Title (EN) CRYSTALLINE FORM OF AN INDAZOLE-CARBOXAMIDE COMPOUND
(FR) FORME CRISTALLINE D'UN COMPOSE D'INDAZOLE/CARBOXAMIDE
Abstract: front page image
(EN)The invention provides crystalline halide salts of 1 isopropyl-1H-indazole-3-carboxylic acid {(1S,3R,5R)-8-[2-(4-acetylpiperazin-1-yl)ethyl]-8-azabicyclo[3.2.1]oct-3-yl}amide and solvates thereof. The invention also provides pharmaceutical compositions comprising such salts, methods of using such crystalline salts to treat diseases associated with 5 HT4 receptor activity, and processes useful for preparing such crystalline salts.
(FR)L'invention concerne des sels d'halogénure cristallins de {(1S,3R,5R)-8-[2-(4-aceéylpipérazin-1-yl)éthyl]-8-azabicyclo[3.2.1]oct-3-yl}amide d'acide 1 isopropyl-1H-indazole-3-carboxylique et des solvates de ceux-ci. L'invention concerne également des compositions pharmaceutiques comprenant de tels sels et des méthodes d'utilisation de tels sels cristallins pour traiter des maladies associées à l'activité du récepteur 5 HT4, ainsi que des procédés utiles pour préparer ces sels cristallins.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)