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Machine translation
1. (WO2006088849) METABOLIC-BASED METHODS FOR MODULATING GENE EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/088849    International Application No.:    PCT/US2006/005141
Publication Date: 24.08.2006 International Filing Date: 14.02.2006
IPC:
C12N 15/11 (2006.01), C12N 15/85 (2006.01), G01N 33/68 (2006.01), A61K 48/00 (2006.01)
Applicants: WISCONSIN ALUMNI RESEARCH FOUNDATION [US/US]; P.O. Box 7365, Madison, WI 53707 (US) (For All Designated States Except US).
ROOPRA, Avtar, S. [GB/US]; (US) (For US Only).
SUTULA, Thomas, P. [US/US]; (US) (For US Only).
SCHOENIKE, Barry [US/US]; (US) (For US Only)
Inventors: ROOPRA, Avtar, S.; (US).
SUTULA, Thomas, P.; (US).
SCHOENIKE, Barry; (US)
Agent: NOONAN, Kevin, S.; MCDONNELL BOEHNEN HULBERT & BERGHOFF LLP, 300 South Wacker Drive, Suite 3100, Chicago, IL 60606 (US)
Priority Data:
60/652,534 14.02.2005 US
Title (EN) METABOLIC-BASED METHODS FOR MODULATING GENE EXPRESSION
(FR) METHODES METABOLIQUES DESTINEES A MODULER L'EXPRESSION GENETIQUE
Abstract: front page image
(EN)This invention provides methods for modulating cellular gene expression for genes operably linked to an NRSE element that is recognized by an NRSF transcriptional repressor, by changing the concentration of reduced nicotinamide adenine dinucleotide (NADH) in the cell.
(FR)L'invention concerne des méthodes destinées à moduler l'expression génétique cellulaire pour des gènes reliés fonctionnels à un élément NRSE reconnu par un répresseur transcriptionnel NRSF par modification de la concentration de nicotinamide adénine dinucléotide réduit (NADH) dans la cellule.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)