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Pub. No.:    WO/2006/088493    International Application No.:    PCT/US2005/024054
Publication Date: 24.08.2006 International Filing Date: 05.07.2005
C12Q 1/68 (2006.01)
Applicants: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY [US/US]; NAVAL RESEARCH LABORORY, 4555 Overlook Avenue, SW, Code 1008.2, Washington, DC 20375 (US) (For All Designated States Except US).
AGAN, Brian [US/US]; (US) (For US Only).
HANSON, Eric, H. [US/US]; (US) (For US Only).
KRUZELOCK, Russell, P. [US/US]; (US) (For US Only).
LIN, Boachuan [US/US]; (US) (For US Only).
ROWLEY, Robb [US/US]; (US) (For US Only).
SETO, Don [US/US]; (US) (For US Only).
STENGER, David [US/US]; (US) (For US Only).
THORNTON, Jennifer [US/US]; (US) (For US Only).
TIBBETTS, Clark [US/US]; (US) (For US Only).
THACH, Dzung [US/US]; (US) (For US Only).
VORA, Gary [US/US]; (US) (For US Only).
WALTER, Elizabeth [US/US]; (US) (For US Only).
WANG, Zheng [US/US]; (US) (For US Only)
Inventors: AGAN, Brian; (US).
HANSON, Eric, H.; (US).
KRUZELOCK, Russell, P.; (US).
LIN, Boachuan; (US).
ROWLEY, Robb; (US).
SETO, Don; (US).
STENGER, David; (US).
THORNTON, Jennifer; (US).
TIBBETTS, Clark; (US).
THACH, Dzung; (US).
VORA, Gary; (US).
WALTER, Elizabeth; (US).
WANG, Zheng; (US)
Agent: KARASEK, John, J.; Associate Counsel (Patents), NAVAL RESEARCH LABORATORY, 4555 Overlook Avenue, SW, Washington, DC 20375-5325 (US)
Priority Data:
60/590,931 02.07.2004 US
60/609,918 15.09.2004 US
60/631,437 29.11.2004 US
60/631,460 29.11.2004 US
60/691,768 16.06.2005 US
Abstract: front page image
(EN)The present invention relates to pathogen detection and identification by use of DNA resequencing microarrays. The present invention also provides resequencing microarray chips for differential diagnosis and serotyping of pathogens present in a biological sample. The present invention further provides methods of detecting the presence and identity of pathogens present in a biological sample. The present invention also provides a computer-implemented biological sequence identifier (CIBSI) system and method for selecting a subsequence from biological sequence data according to at least one selection parameter. The at least one selection parameter corresponds to a likelihood of returning a meaningful result from a similarity search.
(FR)La présente invention concerne la détection et l'identification de pathogènes par utilisation de microréseaux de reséquençage d'ADN. L'invention concerne également des microcircuits de microréseaux de reséquençage destinés au sérotypage et diagnostic différentiels de pathogènes présents dans un échantillon biologique. L'invention concerne en outre des procédés de détection et d'identification de pathogènes dans un échantillon biologique. L'invention concerne aussi un système informatisés d'identifiants de séquences biologiques et un procédé de sélection d'une sous-séquence dans des données de séquence biologique sur la base d'au moins un paramètre de sélection. Ce paramètre de sélection correspond à une vraisemblance de retour de résultat significatif à partir d'une recherche de similitude.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)