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Pub. No.:    WO/2006/088492    International Application No.:    PCT/US2005/023352
Publication Date: 24.08.2006 International Filing Date: 01.07.2005
C12Q 1/68 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORRNIA [US/US]; Office of Technology Transfer, 1111 Franklin Street, 5th Floor, Oakland, California 94607-5200 (US) (For All Designated States Except US).
FELGNER, Philip, L. [US/US]; (US) (For US Only).
DAVIES, Huw [GB/US]; (US) (For US Only).
LING, Xiaowu [US/US]; (US) (For US Only)
Inventors: FELGNER, Philip, L.; (US).
DAVIES, Huw; (US).
LING, Xiaowu; (US)
Agent: FISH, Robert; Rutan & Tucker LLP, 611 Anton Blvd., 14th Fl., Costa Mesa, CA 92628-1950 (US)
Priority Data:
60/585,351 01.07.2004 US
60/638,624 23.12.2004 US
Abstract: front page image
(EN)Methods to obtain expression systems and proteins in a high-throughput protocol by utilizing mixtures of cells cultured from those transformed with a desired nucleotide sequence permit rapide production of protein for use in arrays to assess activity. In one embodiment, the proteins (or peptides) in the array are assessed for their immunological activity with regard to an infectious agent.
(FR)La présente invention concerne des procédés d'obtention de systèmes d'expression et de protéines avec un protocole à grand débit, par utilisation de mélanges de cellules cultivées à partir d'autres cellules transformées avec une séquence nucléotide voulue. Cela permet une production rapide de protéines destinées aux matrices de recherche d'activité. Dans un mode de réalisation, les protéines (ou peptides) dans la matrice font l'objet d'une recherche d'activité immunologique par rapport à un agent infectieux.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)