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Machine translation
1. (WO2006087238) METHOD FOR THE PRODUCTION OF MACROLIDES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/087238    International Application No.:    PCT/EP2006/001673
Publication Date: 24.08.2006 International Filing Date: 21.02.2006
Chapter 2 Demand Filed:    21.09.2006    
IPC:
C07H 17/08 (2006.01)
Applicants: ALPHARMA ApS [DK/DK]; Dalslandsgade 11, DK-2300 Copenhagen (DK) (For All Designated States Except US).
HEGGELUND, Audun [NO/NO]; (NO) (For US Only)
Inventors: HEGGELUND, Audun; (NO)
Agent: COLE, William, Gwyn; HLBBshaw, Merlin House, Falconry Court, Baker's Lane, Epping, Essex CM16 5DQ (GB)
Priority Data:
PA 2005 00262 21.02.2005 DK
Title (EN) METHOD FOR THE PRODUCTION OF MACROLIDES
(FR) PROCEDE DE FABRICATION DE MACROLIDES
Abstract: front page image
(EN)A process for the conversion of 6-11 bridged bicyclic ketolide or erythromycin oximes to 6-11 bridged bicyclic ketolides or erythromycins comprises reacting a 6-11 bridged macrolide with a deoximating agent, preferably an oxidative deoximating agent such as Dess-Martin periodinane. The procedure may comprise deoximation of certain erythromycin A C-9 oxime derivatives with regeneration of the C-9 keto function.
(FR)L'invention porte sur un procédé de conversion d'un cétolide bicyclique ou d'oximes d'érythromycine à pontage 6-11 en cétolides bicycliques ou érythromycines à pontage en 6-11, consistant à faire réagir un macrolide à pontage en 6-11 avec un agent de déoxymation, de préférence un agent de déoxymation oxydant tel que du Dess-Martin periodinane. Ce procédé comprend la déoxymation de certains dérivés d'érythromycine A C-9 oxime accompagnée de la régénération de la fonction C-9 céto.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)