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Machine translation
1. (WO2006086870) APROTININ POLYPEPTIDES FOR TRANSPORTING A COMPOUND ACROSS THE BLOOD-BRAIN BARRIER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/086870    International Application No.:    PCT/CA2005/001158
Publication Date: 24.08.2006 International Filing Date: 21.07.2005
Chapter 2 Demand Filed:    18.12.2006    
IPC:
C12N 15/15 (2006.01), C07K 14/81 (2006.01), A61K 47/48 (2006.01), A61K 47/42 (2006.01), A61K 51/08 (2006.01), A61K 49/14 (2006.01), A61P 25/00 (2006.01)
Applicants: ANGIOCHEM INC. [CA/CA]; 141 Président Kennedy Avenue, Suite SB-5210, Montréal, Québec H2X 3Y7 (CA)
Inventors: BELIVEAU, Richard; (CA).
DEMEULE, Michel; (CA).
CHE, Christian; (CA).
REGINA, Anthony; (CA)
Agent: FORGET, Janique; BCF LLP, 1100 René-Lévesque Blvd. West, 25th Floor, Montréal, Québec H3B 5C9 (CA)
Priority Data:
60/653,928 18.02.2005 US
Title (EN) APROTININ POLYPEPTIDES FOR TRANSPORTING A COMPOUND ACROSS THE BLOOD-BRAIN BARRIER
(FR) POLYPEPTIDES D'APROTININE POUR TRANSPORTER UN COMPOSE A TRAVERS UNE BARRIERE SANG-CERVEAU
Abstract: front page image
(EN)The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptide for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.
(FR)L'invention concerne des améliorations dans le domaine de l'administration de médicaments. En particulier, l'invention concerne des polypeptides dérivés de l'aprotinine et d'analogues d'aprotinine ainsi que des conjugués et des compositions pharmaceutiques renfermant ces polypeptides ou conjugués. La présente invention concerne également l'utilisation de ces polypeptides pour transporter un composé ou un médicament à travers la barrière sang-cerveau d'un mammifère et pour traiter et diagnostiquer des maladies neurologiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)