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Machine translation
1. (WO2006086773) POLYAMINE ANALOGS AS MODULATORS OF CELL MIGRATION AND CELL MOTILITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/086773    International Application No.:    PCT/US2006/005041
Publication Date: 17.08.2006 International Filing Date: 13.02.2006
IPC:
A61K 31/13 (2006.01), A61K 31/131 (2006.01), A61K 31/132 (2006.01), A61K 31/195 (2006.01)
Applicants: CELLGATE, INC. [US/US]; 3 Twin Dolphin Drive, Suite 100, Redwood City, California 94065-1517 (US) (For All Designated States Except US).
TRANSLATIONAL GENOMICS RESEARCH INSTITUTE [US/US]; 445 N. Fifth Street, Suite 600, Phoenix, Arizona 85004 (US) (For All Designated States Except US).
MARTON, Laurence, J. [US/US]; (US) (For US Only).
BERENS, Michael, E. [US/US]; (US) (For US Only).
CLIFFORD, Linda [US/US]; (US) (For US Only)
Inventors: MARTON, Laurence, J.; (US).
BERENS, Michael, E.; (US).
FRYDMAN, Benjamin;
Agent: CERPA, Robert, K.; Morrison & Foerster LLP, 755 Page Mill Road, Palo Alto, California 94304-1018 (US)
Priority Data:
60/652,193 11.02.2005 US
Title (EN) POLYAMINE ANALOGS AS MODULATORS OF CELL MIGRATION AND CELL MOTILITY
(FR) ANALOGUES DE POLYAMINE EN TANT QUE MODULATEURS DE LA MIGRATION CELLULAIRE ET DE LA MOTILITE CELLULAIRE
Abstract: front page image
(EN)This disclosure relates to methods of inhibiting cell motility or cell migration, and of treating diseases involving cell migration or cell motility, using polyamine analogs, such as conformationally restricted polyamine analogs. The diseases to be treated include immune disorders, inflammatory conditions, infection, abnormal immune responses, undesired angiogenesis, tumor cell metastasis or invasion, atherosclerosis, vascular graft occlusion, transplant rejection, other complications of transplants, glomerulonephritis, arthritis, inflammatory responses subsequent to stroke or ischemia, and asthma.
(FR)L'invention concerne des procédés pour inhiber la motilité cellulaire ou la migration cellulaire et pour traiter des maladies impliquant la migration ou la motilité cellulaire, au moyen d'analogues de polyamine tels que des analogues de polyamine à conformation restreinte. Les maladies susceptibles d'être traiter ainsi sont les troubles immunitaires, les troubles inflammatoires, les infections, les réponses immunitaires anormales, l'angiogénèse non désirée, les métastases ou l'invasion de cellules tumorales, l'artériosclérose, l'occlusion par greffe vasculaire, le rejet de greffe, d'autres complications dues à des greffes, la glomérulonéphrite, l'arthrite, les réponses inflammatoires à l'AVC ou l'ischémie et l'asthme.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)