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1. (WO2006086772) DIAGNOSING AND TREATING CANCER USING &bgr;-CATENIN SPLICE VARIANTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/086772    International Application No.:    PCT/US2006/005032
Publication Date: 17.08.2006 International Filing Date: 10.02.2006
IPC:
C12Q 1/68 (2006.01), G01N 33/53 (2006.01)
Applicants: GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; Office of Technology Transfer, National Institutes of Health, 6011 Executive Boulevard, Suite 325, Rockville, Maryland 20852-3804 (US) (For All Designated States Except US).
ROTH, Mark, J. [US/US]; (US) (For US Only).
HUPPI, Konrad [US/US]; (US) (For US Only)
Inventors: ROTH, Mark, J.; (US).
HUPPI, Konrad; (US)
Agent: CORLESS, Peter, F.; EDWARDS ANGELL PALMER & DODGE LLP, P.O. Box 55874, Boston, Massachusetts 02205 (US)
Priority Data:
60/652,154 10.02.2005 US
60/667,084 30.03.2005 US
Title (EN) DIAGNOSING AND TREATING CANCER USING &bgr;-CATENIN SPLICE VARIANTS
(FR) PROCEDE DE DIAGNOSTIC ET DE TRAITEMENT DU CANCER AU MOYEN DE VARIANTS D'EPISSURE DE $G(B)-CATENINE
Abstract: front page image
(EN)The invention relates to method and compositions for treating and diagnosing cancer, in particular &bgr;-catenin related cancers. In general, the methods include administering RNAi constructs. The invention further relates to methods of identifying CTNNBl related cancer therapeutics.
(FR)L'invention concerne un procédé et des compositions destinés à traiter et à diagnostiquer un cancer, plus particulièrement des cancers liés à la ß-caténine. De manière générale, ces procédés consistent à administrer des constructions d'ARNi. Cette invention concerne en outre des procédés d'identification de traitements liés au cancer CTNNB1.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)