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Machine translation
1. (WO2006086769) GIP ANALOG AND HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/086769    International Application No.:    PCT/US2006/005020
Publication Date: 17.08.2006 International Filing Date: 10.02.2006
IPC:
C07K 14/575 (2006.01)
Applicants: AMYLIN PHARMACEUTICALS, INC. [US/US]; 9360 Towne Centre Drive, San Diego, California 92121 (US) (For All Designated States Except US).
LEVY, Odile Esther [US/US]; (US) (For US Only).
HANLEY, Michael R. [US/US]; (US) (For US Only).
JODKA, Carolyn M. [US/US]; (US) (For US Only).
LEWIS, Diana Y. [US/US]; (US) (For US Only).
SOARES, Christopher J. [IN/US]; (US) (For US Only).
GHOSH, Soumitra S. [US/US]; (US) (For US Only).
D'SOUZA, Lawrence J. [IN/US]; (US) (For US Only).
PARKES, David G. [US/US]; (US) (For US Only).
MACK, Christine M. [US/US]; (US) (For US Only).
SRIVASTAVA, Ved [US/US]; (US) (For US Only).
JANSSEN, Samuel [NL/US]; (US) (For US Only).
BARON, Alain D. [US/US]; (US) (For US Only).
YOUNG, Andrew A. [NZ/US]; (US) (For US Only).
PITTNER, Richard A. [GB/US]; (US) (For US Only).
ERICKSON, Mary [US/US]; (US) (For US Only)
Inventors: LEVY, Odile Esther; (US).
HANLEY, Michael R.; (US).
JODKA, Carolyn M.; (US).
LEWIS, Diana Y.; (US).
SOARES, Christopher J.; (US).
GHOSH, Soumitra S.; (US).
D'SOUZA, Lawrence J.; (US).
PARKES, David G.; (US).
MACK, Christine M.; (US).
SRIVASTAVA, Ved; (US).
JANSSEN, Samuel; (US).
BARON, Alain D.; (US).
YOUNG, Andrew A.; (US).
PITTNER, Richard A.; (US).
ERICKSON, Mary; (US)
Common
Representative:
AMYLIN PHARMACEUTICALS, INC.; Intellectual Property Department, 9360 Towne Centre Drive, San Diego, CA 92121 (US)
Priority Data:
60/652,662 11.02.2005 US
60/651,647 11.02.2005 US
60/653,433 15.02.2005 US
60/707,244 11.08.2005 US
60/707,369 11.08.2005 US
60/709,320 17.08.2005 US
60/709,316 17.08.2005 US
Title (EN) GIP ANALOG AND HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES
(FR) ANALOGUES DE GIP ET POLYPEPTIDES HYBRIDES DE GIP AUX PROPRIETES SELECTIONNABLES
Abstract: front page image
(EN)The present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and disorders, for example those which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, positive inotropic effects, reduction of catabolic effects, slowing of gastric emptying. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, critical care, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.
(FR)La présente invention concerne d'une façon générale de nouveaux analogues de GIP et des polypeptides hybrides de GIP aux propriétés sélectionnables, convenant comme agents pour le traitement et la prévention d'affections et de troubles du métabolisme, par exemple ceux qui peuvent être améliorés par une régulation du niveau de glucose dans le plasma, des niveaux d'insuline, et/ou de la sécrétion d'insuline, les effets inotropes positifs, la réduction des effets du catabolisme, et le ralentissement de la vidange gastrique. Les troubles et états concernés sont notamment l'hypertension, la dyslipidémie, les maladies cardiovasculaires, les troubles de l'alimentation, les soins intensifs, la résistance à l'insuline, l'obésité, et le diabète de toute sorte, y-compris de type 1 et de type 2, et le diabète gestationnel.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)