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1. (WO2006086669) APTAMER REGULATED NUCLEIC ACIDS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/086669    International Application No.:    PCT/US2006/004801
Publication Date: 17.08.2006 International Filing Date: 09.02.2006
IPC:
C12N 15/11 (2006.01), C12Q 1/68 (2006.01), C12Q 1/25 (2006.01)
Applicants: CALIFORNIA INSTITUTE OF TECHNOLOGY [US/US]; 1200 East California Boulevard, Pasadena, California 91125 (US) (For All Designated States Except US).
SMOLKE, Christina, D. [US/US]; (US) (For US Only).
BAYER, Travis, S. [US/US]; (US) (For US Only)
Inventors: SMOLKE, Christina, D.; (US).
BAYER, Travis, S.; (US)
Agent: VINCENT, Matthew, P.; ROPES & GRAY LLP, One International Place, Boston, Massachusetts 02110-2624 (US)
Priority Data:
60/651,424 09.02.2005 US
11/243,889 05.10.2005 US
PCT/US2005/036161 05.10.2005 US
Title (EN) APTAMER REGULATED NUCLEIC ACIDS AND USES THEREOF
(FR) ACIDES NUCLEIQUES REGULES PAR DES APTAMERES ET LEURS UTILISATIONS
Abstract: front page image
(EN)The invention relates to aptamer-regulated, ligand-responsive nucleic acids, or 'ampliSwitches,' and uses thereof. Particular embodiments include a ligand- responsive nucleic acid that comprises a primer sequence domain and an aptamer domain that is responsive to a ligand.
(FR)L'invention concerne des acides nucléiques sensibles à des ligands régulés par des aptamères, ou 'ampliSwitches', ainsi que leurs utilisations. Des modes de réalisation particuliers comprennent un acide nucléique sensible à un ligand renfermant un domaine de séquence amorce et un domaine d'aptamère sensible à un ligand.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)