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Pub. No.:    WO/2006/086464    International Application No.:    PCT/US2006/004417
Publication Date: 17.08.2006 International Filing Date: 09.02.2006
C07D 487/04 (2006.01), A61K 31/495 (2006.01), A61K 31/55 (2006.01), A61P 3/04 (2006.01), A61P 3/10 (2006.01), A61P 25/22 (2006.01), A61P 25/24 (2006.01), A61P 25/06 (2006.01), A61P 25/18 (2006.01), A61P 25/20 (2006.01)
Applicants: BRISTOL-MYERS SQUIBB COMPANY [US/US]; P.O. Box 4000, Route 206 And Provinceline Road, Princeton, New Jersey 08543-4000 (US) (For All Designated States Except US).
AHMAD, Saleem [US/US]; (US) (For US Only).
NGU, Khehyong [US/US]; (US) (For US Only)
Inventors: AHMAD, Saleem; (US).
NGU, Khehyong; (US)
Agent: DUNCAN, Sammy G.; Bristol-Myers Squibb Company, P.o. Box 4000, Princeton, New Jersey 08543-4000 (US)
Priority Data:
60/651,833 10.02.2005 US
Abstract: front page image
(EN)The present application provides modulators of serotonin receptors, pharmaceutical compositions containing such modulators and methods for treating various diseases, conditions and disorders associated with modulation of serotonin receptors such as, for example: metabolic diseases, which includes but is not limited to obesity, diabetes, diabetic complications, atherosclerosis, impared glucose tolerance and dyslipidemia; central nervous system diseases which includes but is not limited to, anxiety, depression, obsessive compulsive disorder, panic disorder, psychosis, schizophrenia, sleep disorder, sexual disorder and social phobias; cephalic pain; migraine; and gastrointestinal disorders using such compounds and compositions.
(FR)La présente invention concerne des modulateurs des récepteurs de la sérotonine, des compositions pharmaceutiques contenant ces modulateurs, ainsi que des méthodes dans lesquelles sont utilisés ces composés et ces compositions, destinées au traitement de maladies, d'états et de troubles liés à la modulation des récepteurs de la sérotonine, tels que, par exemple : des maladies métaboliques, comme, notamment, l'obésité, le diabète, des complications diabétiques, l'athérosclérose, la diminution de tolérance au glucose et la dyslipidémie ; des maladies du système nerveux central, comme, notamment, l'anxiété, la dépression, les troubles obsessionnels compulsifs, le trouble panique, la psychose, la schizophrénie, les troubles du sommeil, les troubles sexuels et les phobies sociales ; la céphalée ; la migraine ; et les troubles gastro-intestinaux.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)