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1. (WO2006086449) ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2006/086449 International Application No.: PCT/US2006/004391
Publication Date: 17.08.2006 International Filing Date: 08.02.2006
IPC:
C07D 513/04 (2006.01) ,A61K 31/4365 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
513
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/, C07D477/232
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
4365
the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
Applicants:
COLEY PHARMACEUTICAL GROUP, INC. [US/US]; 93 Worcester Street, Suite 101 Wellesley, Massachusetts 02481, US (AllExceptUS)
PRINCE, Ryan, B. [US/US]; US (UsOnly)
MERRILL, Bryon, A. [US/US]; US (UsOnly)
HEPPNER, Philip, D. [US/US]; US (UsOnly)
KSHIRSAGAR, Tushar, A. [IN/US]; US (UsOnly)
WURST, Joshua, R. [US/US]; US (UsOnly)
MANSKE, Karl, J. [US/US]; US (UsOnly)
RICE, Michael, J. [US/US]; US (UsOnly)
Inventors:
PRINCE, Ryan, B.; US
MERRILL, Bryon, A.; US
HEPPNER, Philip, D.; US
KSHIRSAGAR, Tushar, A.; US
WURST, Joshua, R.; US
MANSKE, Karl, J.; US
RICE, Michael, J.; US
Agent:
GATES, Edward, R.; Wolf, Greenfield & Sacks, P.C. 600 Atlantic Avenue Boston, Massachusetts 02210-2206, US
Priority Data:
60/651,58509.02.2005US
60/733,03603.11.2005US
Title (EN) ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES
(FR) THIAZOLOQUINOLINES ET THIAZOLONAPHTHYRIDINES A SUBSTITUTION ALCOXY
Abstract:
(EN) Thiazoloquinolines and thiazolonaphthyridines with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
(FR) L'invention concerne des thiazoloquinolines et des thiazolonaphthyridines à substituant alcoxy en position 6, 7, 8 ou 9, des compositions pharmaceutiques contenant ces composés, des intermédiaires, des procédés de fabrication et des méthodes d'utilisation de ces composés en tant qu'immunomodulateurs, pour induire la biosynthèse de cytokines chez des animaux, et dans le traitement de maladies, notamment de maladies virales et néoplasiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1846419JP2008530099US20080318998CA2597324ES2475728AU2006212765