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1. (WO2006086396) ANTI-IL-20, ANTI-IL-22 AND ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/086396    International Application No.:    PCT/US2006/004311
Publication Date: 17.08.2006 International Filing Date: 08.02.2006
IPC:
C07K 16/28 (2006.01), C07K 14/715 (2006.01)
Applicants: ZYMOGENETICS, INC. [US/US]; 1201 Eastlake Avenue East, Seattle, WA 98102 (US) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
XU, Wenfeng [CN/US]; (US) (For US Only)
Inventors: XU, Wenfeng; (US)
Agent: WALKER, Shelby, J.; 1201 Eastlake Avenue East, Seattle, WA 98102 (US)
Priority Data:
60/650,830 08.02.2005 US
Title (EN) ANTI-IL-20, ANTI-IL-22 AND ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION
(FR) ANTICORPS ET PARTENAIRES DE LIAISON ANTI-IL-20, ANTI-IL-22 ET ANTI-IL-22RA, ET METHODES D'UTILISATION DE CES ANTICORPS ET PARTENAIRES DE LIAISON DANS DES PROCESSUS INFLAMMATOIRES
Abstract: front page image
(EN)The present invention relates to blocking, inhibiting, reduceing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners.
(FR)L'invention concerne le blocage, l'inhibition, la réduction, l'antagonisation ou la neutralisation de l'activité de molécules polypeptidiques IL-22, IL-20, ou IL-20 et IL-22. IL-20 et IL-22 sont des cytokines impliquées dans des processus inflammatoires et dans des maladies humaines. IL-22RA (zcytor11) est un récepteur commun pour IL-20 et IL-22. L'invention concerne également des anticorps et des partenaires de liaison anti-IL-22RA, ainsi que des méthodes d'antagonisation d'IL-22 ou d'IL-20 et d'IL-22 au moyen de ces anticorps et partenaires de liaison.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)