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Machine translation
1. (WO2006086229) THE USE OF SELECTIVE P2X7 RECEPTOR ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/086229    International Application No.:    PCT/US2006/003865
Publication Date: 17.08.2006 International Filing Date: 03.02.2006
IPC:
A61K 31/381 (2006.01), A61P 25/00 (2006.01), A61P 29/00 (2006.01)
Applicants: ABBOTT LABORATORIES [US/US]; Dept. 377 Bldg Ap6A-1, 100 Abbott Park Road, Abbott Park, Illinois 60064-6008 (US) (For All Designated States Except US).
PEREZ-MEDRANO, Arturo [MX/US]; (US) (For US Only).
NELSON, Derek, W. [US/US]; (US) (For US Only).
CARROLL, William, A. [US/US]; (US) (For US Only).
KORT, Michael, E. [US/US]; (US) (For US Only).
GREGG, Robert, J. [US/US]; (US) (For US Only).
VOIGHT, Eric, A. [US/US]; (US) (For US Only).
JARVIS, Michael, F. [US/US]; (US) (For US Only).
KOWALUK, Elizabeth, A. [AU/US]; (US) (For US Only)
Inventors: PEREZ-MEDRANO, Arturo; (US).
NELSON, Derek, W.; (US).
CARROLL, William, A.; (US).
KORT, Michael, E.; (US).
GREGG, Robert, J.; (US).
VOIGHT, Eric, A.; (US).
JARVIS, Michael, F.; (US).
KOWALUK, Elizabeth, A.; (US)
Agent: FERRARI-DILEO, Gabryleda; Dept. 377 Bldg Ap6a-1, 100 Abbott Park Road, Abbott Park, Illinois 60064-6008 (US)
Priority Data:
60/650,835 08.02.2005 US
Title (EN) THE USE OF SELECTIVE P2X7 RECEPTOR ANTAGONISTS
(FR) UTILISATION D'ANTAGONISTES SELECTIFS DU RECEPTEUR P2X7
Abstract: front page image
(EN)The present invention relates to the use of selective P2X7 receptor antagonists of formula (I), or a pharmaceutically acceptable salt or prodrug thereof wherein D, R1 and R2 are as defined in claim 1, for the treatment of neuropathic pain, chronic inflammatory pain, inflammation, neurodegeneration and for promoting neuroregeneration.
(FR)La présente invention concerne l'utilisation d'antagonistes sélectifs du récepteur P2X7 de formule (I), ou d'un sel ou pro-médicament pharmaceutiquement acceptable de ceux-ci, où D, R1 et R2 dans la formule I sont tels que définis dans la revendication 1, pour le traitement des douleurs neuropathiques, des douleurs chroniques inflammatoires, des inflammations, de la neurodégénérescence et pour favoriser la régénération neuronale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)