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Machine translation
1. (WO2006086105) METHODS AND COMPOSITIONS FOR TREATING INTERVERTEBRAL DISC DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/086105    International Application No.:    PCT/US2006/000788
Publication Date: 17.08.2006 International Filing Date: 11.01.2006
IPC:
C12N 15/00 (2006.01), C07H 21/04 (2006.01), A61K 48/00 (2006.01), C12N 15/63 (2006.01)
Applicants: RUSH UNIVERSITY MEDICAL CENTER [US/US]; Suite 456, 1700 West Van Buren Street, Chicago, Illinois 60612-3244 (US) (For All Designated States Except US).
ANGES MG, INC. [JP/JP]; 7-7-15 Saito-Asagi, Ibaraki, Osaka 567-0085 (JP) (For All Designated States Except US).
MASUDA, Koichi [JP/US]; (US) (For US Only).
GEMBA, Takefumi [JP/JP]; (JP) (For US Only)
Inventors: MASUDA, Koichi; (US).
GEMBA, Takefumi; (JP)
Agent: MEARA, Joseph P.; FOLEY & LARDNER LLP, 150 East Gilman Street, Post Office Box 1497, Madison, Wisconsin 53701-1497 (US)
Priority Data:
11/033,466 11.01.2005 US
Title (EN) METHODS AND COMPOSITIONS FOR TREATING INTERVERTEBRAL DISC DISORDERS
(FR) METHODES ET COMPOSITIONS DESTINEES A TRAITER, INHIBER ET INVERSER DES DISCOPATHIES INTERVERTEBRALES
Abstract: front page image
(EN)Described herein are methods and compositions for inhibiting, treating and reversing intervertebral disc disorders using transcription factor inhibitors. In certain embodiments, the transcription factor inhibitor targets the transcription factor NF-ϰB. Also described are methods and compositions where intervertebral disc disorder is reversed using a decoy oligodeoxy-nucleotide that blocks NF-ϰB.
(FR)L'invention concerne des méthodes et des compositions destinées à inhiber, traiter et inverser des discopathies intervertébrales au moyen d'inhibiteurs de facteurs de transcription. Dans certains modes de réalisation, l'inhibiteur de facteur de transcription est ciblé sur le facteur de transcription NF-?B. L'invention concerne également des méthodes et des compositions permettant d'inverser une discopathie intervertébrale au moyen d'un oligodésoxynucléotide leurre bloquant NF-?B.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)