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Machine translation
1. (WO2006085959) FUSION PROTEINS COMPRISING CD4 MINIMAL MODULES AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/085959    International Application No.:    PCT/US2005/022801
Publication Date: 17.08.2006 International Filing Date: 08.06.2005
IPC:
A61K 39/00 (2006.01)
Applicants: NOVARTIS VACCINES AND DIAGNOSTICS INC. [US/US]; 4560 Horton Street, Emeryville, California 94608 (US) (For All Designated States Except US).
MASIGNANI, Vega [IT/US]; (US) (For US Only).
SCARSELLI, Maria [IT/US]; (US) (For US Only).
CAPECCHI, Barbara [IT/US]; (US) (For US Only).
SHARMA, Victoria [US/US]; (US) (For US Only).
BARNETT, Susan W. [US/US]; (US) (For US Only).
SRIVASTAVA, Indresh K. [IN/US]; (US) (For US Only).
RAPPUOLI, Rino [IT/US]; (US) (For US Only)
Inventors: MASIGNANI, Vega; (US).
SCARSELLI, Maria; (US).
CAPECCHI, Barbara; (US).
SHARMA, Victoria; (US).
BARNETT, Susan W.; (US).
SRIVASTAVA, Indresh K.; (US).
RAPPUOLI, Rino; (US)
Agent: LEE, Helen; Novartis Vaccines and Diagnostics Inc., P.O. Box 8097, Emeryville, CA 94662-8097 (US)
Priority Data:
60/578,211 08.06.2004 US
60/578,151 08.06.2004 US
Title (EN) FUSION PROTEINS COMPRISING CD4 MINIMAL MODULES AND METHODS OF USE THEREOF
(FR) PROTEINES DE FUSION COMPRENANT DES MODULES CD4 MINIMAUX, ET PROCEDES D'UTILISATION CORRESPONDANTS
Abstract: front page image
(EN)Fusion proteins comprising CD4 minimal modules that bind to HIV Env polypeptides in a non-CD4 backbone are described. Also described are complexes of these fusion proteins with Env as well as methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided.
(FR)La présente invention concerne des protéines de fusion comprenant des modules CD4 minimaux se liant aux polypeptides Env du VIH dans une ossature non CD4. L'invention concerne également des complexes de ces protéines de fusion avec l'Env ainsi que des procédés permettant le diagnostic, le traitement et la prévention au moyen de ces polynucléotides et polypeptides.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)