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Pub. No.:    WO/2006/083979    International Application No.:    PCT/US2006/003588
Publication Date: 10.08.2006 International Filing Date: 02.02.2006
A61K 9/00 (2006.01), A61P 35/00 (2006.01), A61K 31/65 (2006.01), A61K 31/196 (2006.01)
Applicants: NEXGENIX PHARMACEUTICALS, L.L.C. [US/US]; 152 West 57th Street, Suite 11B, New York, New York 10019 (US) (For All Designated States Except US).
CHEN, Ruihong [US/US]; (US) (For US Only).
RUBENSTEIN, Allan, E. [US/US]; (US) (For US Only).
SHEN, Xiaodong [CN/US]; (US) (For US Only).
STEWART, Scott [US/US]; (US) (For US Only).
YU, Jin-Chen [US/US]; (US) (For US Only)
Inventors: CHEN, Ruihong; (US).
RUBENSTEIN, Allan, E.; (US).
SHEN, Xiaodong; (US).
STEWART, Scott; (US).
YU, Jin-Chen; (US)
Agent: HULEATT, Jayme, A.; COOLEY GODWARD, LLP, One Freedom Square, Reston Town Center, Reston, Virginia 20190-5656 (US)
Priority Data:
60/649,854 02.02.2005 US
60/669,813 07.04.2005 US
Abstract: front page image
(EN)A method for treating a neurofibroma, e.g. dermal neurofibroma, a subdermal neurofibroma, or a superficial plexiform neurofibroma, in a subject in need of such treatment is disclosed. The method comprises locally applying a composition to a neurofibroma either topically or intralesionally. This method does not encompass systemic administration of the composition to the subject to have an effect on the neurofibromas. Compositions useful for such treatments and methods of preparing the compositions are disclosed.
(FR)L'invention concerne une méthode de traitement d'un neurofibrome, par exemple un neurofibrome cutané, un neurofibrome sous-cutané ou un neurofibrome plexiforme superficiel, chez un patient nécessitant un tel traitement. Cette méthode consiste à appliquer localement une composition sur un neurofibrome, topiquement ou intralésionnellement. La méthode selon l'invention ne concerne pas l'administration systémique de la composition au patient pour obtenir un effet sur les neurofibromes. L'invention concerne également des compositions utiles pour ces traitements, ainsi que des procédés de préparation associés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)