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Machine translation
1. (WO2006083969) BLOOD ANALYSIS USING A FLOW IMAGING CYTOMETER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/083969    International Application No.:    PCT/US2006/003573
Publication Date: 10.08.2006 International Filing Date: 01.02.2006
Chapter 2 Demand Filed:    30.08.2006    
IPC:
G06K 9/00 (2006.01)
Applicants: AMNIS CORPORATION [US/US]; 2505 Third Avenue, Suite 210, Seattle, WA 98121 (US) (For All Designated States Except US).
ORTYN, William [US/US]; (US) (For US Only).
BASIJI, David [US/US]; (US) (For US Only).
GEORGE, Thaddeous [US/US]; (US) (For US Only).
MORRISSEY, Philip [US/US]; (US) (For US Only).
HALL, Brian [US/US]; (US) (For US Only).
PERRY, David [US/US]; (US) (For US Only).
ZIMMERMAN, Cathleen [US/US]; (US) (For US Only)
Inventors: ORTYN, William; (US).
BASIJI, David; (US).
GEORGE, Thaddeous; (US).
MORRISSEY, Philip; (US).
HALL, Brian; (US).
PERRY, David; (US).
ZIMMERMAN, Cathleen; (US)
Agent: KING, Michael; Law Offices of Ronald M. Anderson, Suite 507, 600 108th Avenue NE, Bellevue, WA 98004 (US)
Priority Data:
60/649,373 01.02.2005 US
Title (EN) BLOOD ANALYSIS USING A FLOW IMAGING CYTOMETER
(FR) ANALYSE SANGUINE ET CELLULAIRE AU MOYEN D'UN CYTOMETRE EN FLUX IMAGEUR
Abstract: front page image
(EN)Multimodal/multispectral images of a population of cells are simultaneously collected (402). Photometric and/or morphometric features identifiable in the images (404) are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation (408). Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.
(FR)On collecte des images multimodales/multispectrales d'une population de cellules. On utilise des caractéristiques photométriques et/ou morphométriques identifiables dans les images pour diviser la population de cellules en une pluralité de sous populations. Si la population de cellules comprend des cellules malades et des cellules saines, les images peuvent être divisées en une sous population saine et en une sous population malade. Si la population de cellules ne comprend pas de cellules malades, un ou plusieurs ratios de différents types de cellules chez des patients ne présentant pas d'état pathologique peuvent être comparés aux ratios correspondants chez des patients présentant l'état pathologique, ce qui permet de détecter ledit état pathologique. Des cellules sanguines peuvent par exemple être divisées en différents types en fonction de leurs images et une augmentation du nombre de lymphocytes, un phénomène associé à la leucémie lymphoïde chronique peut être détectée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)