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1. (WO2006083090) PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING RESTENOSIS COMPRISING PEROXIREDOXIN 2 PROTEIN AS AN ACTIVE INGREDIENT AND COMPOSITION FOR SCREENING THERAPEUTICS OF RESTENOSIS COMPRISING PEROXIREDOXIN 2 GENE OR ITS PROTEIN PRODUCT, AND METHOD FOR SCREENING THERAPEUTICS OF RESTENOSIS USING SAID COMPOSITION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/083090    International Application No.:    PCT/KR2006/000289
Publication Date: 10.08.2006 International Filing Date: 25.01.2006
Chapter 2 Demand Filed:    31.08.2006    
IPC:
A61K 38/16 (2006.01)
Applicants: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION [KR/KR]; Ewha Womans University, 11-1,, Daehyeon-dong, Seodaemoon-ku,, Seoul 120-750 (KR) (For All Designated States Except US).
KANG, Sang-Won [KR/KR]; (KR) (For US Only).
CHOI, Min-Hee [KR/KR]; (KR) (For US Only)
Inventors: KANG, Sang-Won; (KR).
CHOI, Min-Hee; (KR)
Agent: DARAE PATENT FIRM; 10th Floor, KIPS,, 647-9, Yeoksam-dong, Kangnam-ku,, Seoul 135-980 (KR)
Priority Data:
10-2005-0009875 03.02.2005 KR
Title (EN) PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING RESTENOSIS COMPRISING PEROXIREDOXIN 2 PROTEIN AS AN ACTIVE INGREDIENT AND COMPOSITION FOR SCREENING THERAPEUTICS OF RESTENOSIS COMPRISING PEROXIREDOXIN 2 GENE OR ITS PROTEIN PRODUCT, AND METHOD FOR SCREENING THERAPEUTICS OF RESTENOSIS USING SAID COMPOSITION
(FR) COMPOSITION PHARMACEUTIQUE POUR LA PREVENTION ET LE TRAITEMENT DE LA RESTENOSE, COMPRENANT DE LA PEROXIREDOXINE 2 PROTEINE COMME INGREDIENT ACTIF, ET COMPOSITION POUR THERAPIES PAR CRIBLAGE DE LA RESTENOSE COMPRENANT LE GENE DE PEROXIREDOXINE 2 OU SON PRODUIT PROTEINIQUE, ET PROCEDE POUR THERAPIES PAR CRIBLAGE DE LA RESTEN
Abstract: front page image
(EN)Disclosed herein is a pharmaceutical composition for the prophylaxis and treatment of restenosis, comprising a peroxiredoxin 2(Prx II) protein as an active ingredient. Optionally, the composition may contain other active ingredients suppressive of restenosis at the carotid artery, the coronary artery, the peripheral artery, and the renal artery. Also, a composition and a method are provided for screening therapeutics for restenosis. This screening composition comprises a peroxiredoxin 2 gene or protein. Together with the method, the composition is useful for searching and developing therapeutics for restenosis.
(FR)L'invention concerne une composition pharmaceutique pour la prophylaxie et le traitement de la resténose, comprenant une peroxiredoxine 2 (Prx II) protéine comme ingrédient actif. En variante, la composition peut contenir d'autres ingrédients actifs suppresseurs de resténose à l'artère carotide, l'artère coronaire, l'artère périphérique et l'artère rénale. L'invention concerne en outre une composition et un procédé pour thérapies par criblage de la resténose. Cette composition de criblage comprend un gène ou une protéine de peroxiredoxine 2. Conjointement avec ce procédé, la composition est utilisée pour la recherche et le développement d'agents thérapeutiques de la resténose.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Korean (KO)