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1. (WO2006082974) REMEDY FOR ISCHEMIC DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/082974    International Application No.:    PCT/JP2006/302022
Publication Date: 10.08.2006 International Filing Date: 07.02.2006
IPC:
A61K 45/00 (2006.01), A61K 39/395 (2006.01), A61P 7/02 (2006.01), A61P 9/00 (2006.01)
Applicants: CHUGAI SEIYAKU KABUSHIKI KAISHA [JP/JP]; 5-1, Ukima 5-chome, Kita-ku, Tokyo 1158543 (JP) (For All Designated States Except US).
NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE [JP/JP]; 20-1, Handayama 1-chome, Hamamatsu-shi, Shizuoka 4313192 (JP) (For All Designated States Except US).
UMEMURA, Kazuo [JP/JP]; (JP) (For US Only).
MUTO, Atsushi [JP/JP]; (JP) (For US Only).
IKEDA, Sachiya [JP/JP]; (JP) (For US Only)
Inventors: UMEMURA, Kazuo; (JP).
MUTO, Atsushi; (JP).
IKEDA, Sachiya; (JP)
Agent: SHAMOTO, Ichio; YUASA AND HARA Section 206, New Ohtemachi Bldg. 2-1, Ohtemachi 2-chome Chiyoda-ku, Tokyo 100-0004 (JP)
Priority Data:
2005-030836 07.02.2005 JP
Title (EN) REMEDY FOR ISCHEMIC DISEASE
(FR) REMEDE POUR UNE MALADIE ISCHEMIQUE
(JA) 虚血性疾患治療剤
Abstract: front page image
(EN)A medicinal composition containing a tissue factor inhibitor which is to be administered after the onset of a thromboembolic ischemic disease, in particular, after thrombus or embolus formation; a secondary thrombus formation inhibitor containing a tissue factor inhibitor which is to be administered after the primary thrombus formation; an inhibitor for lowering in blood flow containing a tissue factor inhibitor which is to be administered after thrombus or embolus formation; and a method of preventing secondary thrombus formation which comprises inhibiting the function of a tissue factor after the primary thrombus formation.
(FR)La présente invention concerne une composition médicamenteuse contenant un inhibiteur de facteur tissulaire devant être administré après l’apparition d’une maladie ischémique thromboembolique, en particulier après la formation d'un thrombus ou d'un embole ; un inhibiteur de la formation d’un thrombus secondaire contenant un inhibiteur de facteur tissulaire devant être administré après la formation du thrombus primaire ; un inhibiteur permettant d’abaisser le débit sanguin contenant un inhibiteur de facteur tissulaire devant être administré après la formation du thrombus ou de l'embole; et un procédé de prévention de la formation d’un thrombus secondaire qui comprend l’étape consistant à inhiber la fonction d’un facteur tissulaire après la formation d’un thrombus primaire.
(JA) 本発明は、血栓塞栓性虚血性疾患の発症後、特に血栓又は塞栓形成後に投与するための、組織因子阻害物質を含む医薬組成物、一次血栓形成後に投与するための組織因子阻害物質を含む複次血栓形成抑制剤、血栓又は塞栓形成後に投与するための組織因子阻害物質を含む血流低下抑制剤、および一次血栓形成後に組織因子の作用を阻害することにより複次血栓の形成を抑制する方法に関する。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)