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1. (WO2006082501) FAST WET-MASSING METHOD FOR THE PREPARATION OF CALCIUM-CONTAINING COMPOSITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/082501    International Application No.:    PCT/IB2006/000195
Publication Date: 10.08.2006 International Filing Date: 02.02.2006
Chapter 2 Demand Filed:    03.01.2007    
IPC:
A61K 9/16 (2006.01), A61K 9/20 (2006.01), A61K 33/06 (2006.01)
Applicants: NYCOMED PHARMA AS [NO/NO]; Drammensveien 852, NO-1385 Asker (NO) (For All Designated States Except US).
BERTELSEN, Poul, Egon [DK/DK]; (DK) (For US Only).
OLSEN, Peder, Mohr [DK/DK]; (DK) (For US Only).
NIELSEN, Carsten, Martini [DK/DK]; (DK) (For US Only).
TOLLESHAUG, Magnus, Wilhelm [NO/DK]; (DK) (For US Only)
Inventors: BERTELSEN, Poul, Egon; (DK).
OLSEN, Peder, Mohr; (DK).
NIELSEN, Carsten, Martini; (DK).
TOLLESHAUG, Magnus, Wilhelm; (DK)
Agent: ALBIHNS A/S; H.C. Andersens Boulevard 49, DK-1553 Copenhagen V (DK)
Priority Data:
PA 2005 00168 03.02.2005 DK
Title (EN) FAST WET-MASSING METHOD FOR THE PREPARATION OF CALCIUM-CONTAINING COMPOSITIONS
(FR) PROCEDE DE FORMATION RAPIDE DE MASSE HUMIDE POUR LA PREPARATION DE COMPOSITIONS CONTENANT DU CALCIUM
Abstract: front page image
(EN)The present invention relates to a novel process for the preparation of a granulate comprising a calcium-containing compound as an active substance. The method comprises a method for the preparation of a granulate comprising a calcium-containing compound as an active substance, the method comprising, i) feeding a granulation chamber with a composition comprising the calcium-containing compound, ii) wet-massing the composition with a granulation liquid optionally comprising a pharmaceutically acceptable binder for a time period of at the most 30 sec to obtain a wet granulate, iii) drying the thus obtained wet granulate. A granulate obtained by the present method is especially suitable in the preparation of solid dosage forms, in particular in the preparation of tablets.
(FR)L'invention concerne un nouveau procédé de préparation d'un granulé comprenant un composé contenant du calcium comme principe actif. Le procédé comprend un procédé de préparation d'un granulé contenant un composé contenant du calcium comme principe actif et consiste: i) à alimenter une chambre de granulation avec une composition renfermant le composé contenant du calcium, ii) à former une masse humide de la composition avec un liquide de granulation renfermant éventuellement un liant pharmaceutiquement acceptable pendant une certaine période de temps ne dépassant pas 30 secondes afin d'obtenir un granulé humide, iii) à sécher le granulé humide ainsi obtenu. Un granulé obtenu par cette invention trouve une application dans la préparation de posologie solides, plus particulièrement dans la préparation de comprimés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)