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Machine translation
1. (WO2006082279) PROCESS FOR THE MANUFACTURING OF 7-ETHYL-10-HYDROXY CAMPTOTHECIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/082279    International Application No.:    PCT/FI2006/000034
Publication Date: 10.08.2006 International Filing Date: 06.02.2006
IPC:
C07D 491/22 (2006.01)
Applicants: FERMION OY [FI/FI]; Koivu-Mankkaan tie 6 A, FI-02200 Espoo (FI) (For All Designated States Except US).
LAITINEN, Ilpo [FI/FI]; (FI) (For US Only)
Inventors: LAITINEN, Ilpo; (FI)
Agent: ORION CORPORATION ORION PHARMA; Legal Affairs and Intellectual Property Rights, P.O. Box 65, FI-02101 Espoo (FI)
Priority Data:
60/650,175 07.02.2005 US
Title (EN) PROCESS FOR THE MANUFACTURING OF 7-ETHYL-10-HYDROXY CAMPTOTHECIN
(FR) PROCEDE DE FABRICATION DE CAMPTOTHECINE 7-ETHYL-10-HYDROXY
Abstract: front page image
(EN)The invention discloses the preparation method of 7-ethyl-l0-hydroxycamptothecin from 4-ethyl-7, 8-dihydro-4-hydroxy-lH-pyrano [3,4-f ] indolizine-3, 6,10 (4H) -trione and 1- (2-amino-5-hydroxyphenyl) -propan-1-one using high reaction temperature and fast heating to that temperature .
(FR)L'invention concerne un procédé de préparation de 7-éthyl-10-hydroxycamptothécine à partir de 4-éthyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione et 1-(2-amino-5-hydroxyphényle)-propane-1-one qui utilise une température de réaction supérieure et un chauffage plus rapide à cette température.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)