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Pub. No.:    WO/2006/081665    International Application No.:    PCT/CA2006/000140
Publication Date: 10.08.2006 International Filing Date: 03.02.2006
C07H 19/173 (2006.01), C07H 19/167 (2006.01), A61P 31/04 (2006.01), A61K 31/7076 (2006.01)
Applicants: UTI LIMITED PARTNERSHIP [CA/CA]; 130, 3553 31st Street Nw, Calgary, Alberta T2L 2K7 (CA) (For All Designated States Except US).
SNYDER, Floyd, Frederick [CA/CA]; (CA) (For US Only).
BACK, Thomas, George [CA/CA]; (CA) (For US Only)
Inventors: SNYDER, Floyd, Frederick; (CA).
BACK, Thomas, George; (CA)
Agent: BENNETT JONES LLP; Attention: Irene T. Bridger, 4500 Bankers Hall East, 855 2nd Street Sw, Calgary, Alberta T2P 4K7 (CA)
Priority Data:
60/593,678 04.02.2005 US
Abstract: front page image
(EN)The present invention is directed to purine nucleoside analogs of the general Formula (I), or tautomers thereof, physiologically acceptable salts, solvents and physiologically functional derivatives thereof, and pharmaceutical compositions comprising such compounds, salts and derivatives, which are useful as anti-bacterial and anti-protozoan agents. The invention is also directed to methods for treating a bacterial or protozoan infection in a mammal and use of the compounds for inhibiting the growth of a bacteria or protozoa.
(FR)La présente invention concerne des analogues nucléosidiques puriques de formule générale (I), ou des tautomères de ces derniers, des sels physiologiquement acceptables, des solvants et des dérivés physiologiquement fonctionnels de ces derniers, ainsi que des compositions pharmaceutiques comprenant lesdits composés, sels et dérivés, utiles comme agents antibactériens et antiprotozoaires. Cette invention concerne également des méthodes pour traiter une infection bactérienne ou protozoaire chez un mammifère et l'utilisation desdits composés pour inhiber la croissance d'une bactérie ou d'un protozoaire.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)