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Machine translation
1. (WO2006081658) IN SILICO SCREENING FOR SHBG BINDING LIGANDS VIA PHARMACOPHORE MODELS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/081658    International Application No.:    PCT/CA2006/000130
Publication Date: 10.08.2006 International Filing Date: 01.02.2006
IPC:
G01N 33/74 (2006.01), G01N 33/53 (2006.01), G01N 33/15 (2006.01), A61K 31/56 (2006.01), A61K 31/44 (2006.01), A61K 31/353 (2006.01), A61K 31/352 (2006.01), G06F 19/00 (2006.01)
Applicants: THE UNIVERSITY OF BRITISH COLUMBIA [CA/CA]; University - Industry Liaison Office, #103,6190 Agronomy Road, Vancouver, British Columbia V6T 1Z3 (CA) (For All Designated States Except US).
HAMMOND, Geoffrey, L. [CA/CA]; (CA) (For US Only).
SHI, Zheng [CA/CA]; (CA) (For US Only).
FALLAHI, Magid [CA/CA]; (CA) (For US Only).
CHERKASOV, Artem [CA/CA]; (CA) (For US Only)
Inventors: HAMMOND, Geoffrey, L.; (CA).
SHI, Zheng; (CA).
FALLAHI, Magid; (CA).
CHERKASOV, Artem; (CA)
Agent: SMART & BIGGAR; Box 11560, Vancouver Centre, Suite 2200, 650 West Georgia Street, Vancouver, British Columbia V6B 4N8 (CA)
Priority Data:
60/648,384 01.02.2005 US
Title (EN) IN SILICO SCREENING FOR SHBG BINDING LIGANDS VIA PHARMACOPHORE MODELS
(FR) CRIBLAGE IN SILICO POUR DES LIGANDS DE LIAISON A LA GLOBULINE DE LIAISON DES HORMONES SEXUELLES GRACE A DES MODELES DE PHARMACOPHORES
Abstract: front page image
(EN)Provides methods for identifying and using ligands for the sex hormone binding site of sex hormone binding globulin (SHBG) as well as such novel ligands are provided. Also provided are compositions comprising such ligands for use in modifying sex hormone binding to SHBG. Further provided is a computer implemented method for identifying SHBG ligands and data structures embodied in computer readable media useful in such a method. SHBG ligands comprise a defined pharmacophore.
(FR)La présente invention a trait à des procédés pour l'identification et l'utilisation de ligands pour le site de liaison d'hormones sexuelles de globuline de liaison des hormones sexuelles (SHBG) ainsi qu'à de tels nouveaux ligands. L'invention a également trait à des compositions comportant de tels ligands destinés à être utilisés pour la modification de liaison des hormones sexuelles à la SHBG. L'invention a trait en outre à un procédé mis en oeuvre par ordinateur pour l'identification de ligands SHBG et des structures de données incorporées dans des supports lisibles par ordinateur utiles dans un tel procédé. Les ligands SHBG comportent un phamacophore défini.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)