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Machine translation
1. (WO2006081366) METHOD AND APPARATUS FOR MUSCLE FUNCTION MEASUREMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/081366    International Application No.:    PCT/US2006/002813
Publication Date: 03.08.2006 International Filing Date: 26.01.2006
IPC:
A61B 5/0215 (2006.01)
Applicants: MEDTRONIC, INC. [US/US]; MS LC340, 710 Medtronic Parkway, Minneapolis, Minnesota 55432 (US) (For All Designated States Except US).
KARAMANOGLU, Mustafa [US/US]; (US) (For US Only).
SPLETT, Vincent, E. [US/US]; (US) (For US Only).
BENNETT, Tommy, D. [US/US]; (US) (For US Only)
Inventors: KARAMANOGLU, Mustafa; (US).
SPLETT, Vincent, E.; (US).
BENNETT, Tommy, D.; (US)
Agent: MCDOWALL, Paul, H.; MS LC340, 710 Medtronic Parkway, Minneapolis, Minnesota 55432, (US)
Priority Data:
11/043,819 26.01.2005 US
Title (EN) METHOD AND APPARATUS FOR MUSCLE FUNCTION MEASUREMENT
(FR) PROCEDE ET APPAREIL DE MESURE DE LA FONCTION MUSCULAIRE
Abstract: front page image
(EN)The present invention provides an apparatus and method for monitoring muscle function based on an index derived from a pressure or force signal. The muscle function index is derived from an instantaneous muscle stiffness ratio computed as the ratio of the first time derivative of the pressure or force waveform to the corresponding instantaneous pressure or force. The instantaneous stiffness ratio, Ė/E(t), is in units of 1/sec and relates to the rate of strong bond formation and will be influenced by calcium handling properties of the muscle fibers and the intracellular calcium concentration. As such, an index derived from Ė/E(t) provides a measure of the inotropic status of the muscle.
(FR)L'invention porte sur un appareil et un procédé qui permettent de surveiller la fonction musculaire sur la base d'un indice dérivé d'un signal de pression ou de force. L'indice de fonction musculaire est dérivé d'un rapport de rigidité musculaire instantanée calculé comme le rapport entre la première dérivée temporelle de la forme d'onde de pression ou de force et la pression ou la force instantanée correspondante. Le rapport de rigidité instantanée, E/E(t), s'exprime en unités de 1/sec, est lié au taux de formation de liaisons solides et sera influencé par les propriétés de gestion du calcium des fibres musculaires et par la concentration de calcium intracellulaire. En tant que tel, un indice dérivé de E/E(t) fournit une mesure de l'état inotropique du muscle.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)