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Machine translation
1. (WO2006081337) ERASTIN ANALOGUES AND THEIR USES FOR KILLING CANCER CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/081337    International Application No.:    PCT/US2006/002723
Publication Date: 03.08.2006 International Filing Date: 25.01.2006
IPC:
C07D 239/88 (2006.01), C07D 239/91 (2006.01), C07D 405/12 (2006.01), C07D 409/12 (2006.01), A61K 31/517 (2006.01), A61P 35/00 (2006.01)
Applicants: WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH [US/US]; Nine Cambridge Center, Cambridge, Massachusetts 01242-1479 (US) (For All Designated States Except US).
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK [US/US]; West 116th Street And Broadway, New York, New York 10027 (US) (For All Designated States Except US).
STOCKWELL, Brent, R. [US/US]; (US) (For US Only)
Inventors: STOCKWELL, Brent, R.; (US)
Agent: HALSTEAD, David, P.; FISH & NEAVE IP GROUP, ROPES & GRAY LLP, One International Place, Boston, Massachusetts 02110-2624 (US)
Priority Data:
60/647,372 25.01.2005 US
60/762,221 24.01.2006 US
Title (EN) ERASTIN ANALOGUES AND THEIR USES FOR KILLING CANCER CELLS
(FR) ERASTINE ET PROTEINES DE LIAISON D'ERASTINE, ET UTILISATIONS DE CELLES-CI
Abstract: front page image
(EN)The invention provides methods for effective killing of cancer cells with erastin and related compounds or derivatives.
(FR)L'invention concerne des méthodes permettant de cribler des partenaires de liaison, en particulier, des partenaires de liaison essentiels pour l'activité biologique de l'érastine (par exemple, des VDAC tels que VDAC3). L'invention concerne également des réactifs et des méthodes permettant de tuer efficacement les cellules cancéreuses à l'aide de l'érastine ainsi que des composés et des dérivés correspondant.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)