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Machine translation
1. (WO2006081311) COMPOSITIONS AND METHODS FOR THE INTRACELLULAR DISRUPTION OF VEGF AND VEGFR-2 BY INTRACEPTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/081311    International Application No.:    PCT/US2006/002684
Publication Date: 03.08.2006 International Filing Date: 26.01.2006
IPC:
C12Q 1/68 (2006.01), C07H 21/04 (2006.01)
Applicants: MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE [US/US]; 1120 15th Street, Augusta, Georgia 30912 (US) (For All Designated States Except US).
AMBATI, Balamurali [US/US]; (US) (For US Only).
SINGH, Nirbhai [IN/US]; (US) (For US Only).
AMIN, Shivan [US/US]; (US) (For US Only)
Inventors: AMBATI, Balamurali; (US).
SINGH, Nirbhai; (US).
AMIN, Shivan; (US)
Agent: WARREN, William, L.; Sutherland Asbill & Brennan LLP, 999 Peachtree Street, NE, Atlanta, Georgia 30309-3996 (US)
Priority Data:
60/647,224 26.01.2005 US
Title (EN) COMPOSITIONS AND METHODS FOR THE INTRACELLULAR DISRUPTION OF VEGF AND VEGFR-2 BY INTRACEPTORS
(FR) COMPOSITIONS ET METHODES DE DISRUPTION INTRACELLULAIRE DE VEGF ET DE VEGFR-2 A L'AIDE DE RECEPTEURS INTRACELLULAIRES
Abstract: front page image
(EN)The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
(FR)L'invention concerne un récepteur intracellulaire interagissant avec VEGF et/ou VEGFR et réduisant leur activité, qui permet de traiter des états associés à l'angiogénèse. L'invention concerne également des compositions pharmaceutiques et leurs méthodes d'utilisation pour traiter et prévenir un état associé à l'angiogénèse à l'aide desdits récepteur intracellulaire. L'invention concerne enfin des acides nucléiques codant pour ces intracepteurs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)