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1. (WO2006081210) MEDICAL DEVICE WITH DRUG RELEASE REGIONS CONTAINING PSEUDO - BLOCK COPOLYMERS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2006/081210 International Application No.: PCT/US2006/002348
Publication Date: 03.08.2006 International Filing Date: 25.01.2006
IPC:
A61L 31/04 (2006.01) ,A61L 31/10 (2006.01) ,A61L 31/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
04
Macromolecular materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
08
Materials for coatings
10
Macromolecular materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
04
Macromolecular materials
06
obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
Applicants:
RICHARD, Robert E. [US/US]; US (UsOnly)
BOSTON SCIENTIFIC SCIMED, INC. [US/US]; One Scimed Place Maple Grove, MN 55311, US (AllExceptUS)
Inventors:
RICHARD, Robert E.; US
Agent:
PARK, Keum J. ; MAYER & WILLIAMS, PC 251 North Avenue West, 2nd Floor Westfield, NJ 07090, US
Priority Data:
11/042,03725.01.2005US
Title (EN) MEDICAL DEVICE WITH DRUG RELEASE REGIONS CONTAINING PSEUDO - BLOCK COPOLYMERS
(FR) REGIONS DE LIBERATION DE MEDICAMENTS DE DISPOSITIF MEDICAL CONTENANT DES POLYMERES LIES PAR UNE LIAISON NON COVALENTE
Abstract:
(EN) According to one aspect, implantable or insertable medical devices are provided, which contain polymeric release regions that release one or more therapeutic agents. The polymeric release regions, in turn, contain the following: (i) a first bonding polymer having a first polymer block and a first bonding group and (ii) a second bonding polymer having a second polymer block and a second bonding group. A therapeutic agent is disposed beneath or within the polymeric release region. The first and second polymer blocks can be the same as or different from one another, as can the first and second bonding groups. The first and second bonding groups are bound to one another via non- covalent bonding, for example, via electrostatic interaction, coordinative bonds, &pgr;-&pgr; stacking, or hydrogen bonding. According to another aspect, implantable or insertable medical devices are provided, which have a polymeric region that comprises (a) a first polymer having a first polymer block and a first bonding group and (b) a therapeutic agent having a bonding group that bonds to said first bonding group via non-covalent bonding at ambient temperature.
(FR) Selon un aspect, l'invention concerne des dispositifs médicaux implantables ou insérables, contenant des régions de libération polymériques qui libèrent un ou plusieurs agents thérapeutiques. Les régions de libération polymérique contiennent, à leur tour, les éléments suivants: (I) un premier polymère de liaison comprenant un premier bloc polymère et un premier groupe de liaison; et (ii) un second polymère de liaison comprenant un second bloc polymère et un second groupe de liaison. Un agent thérapeutique est disposé sous ou à l'intérieur de la région de libération polymérique. Le premier et le second bloc polymère peuvent être les mêmes ou différents, de même que le premier et le second groupe de liaison. Le premier et le second groupe de liaison sont liés entre eux par une liaison non covalente, par exemple par une interaction électrostatique, des liaisons coordinatives, un empilement p-p, ou une liaison hydrogène. Selon encore un autre aspect, l'invention se rapporte à des dispositifs médicaux implantables ou insérables, comprenant une région polymérique qui comprend: (a) un premier polymère comprenant un premier bloc polymère et un premier groupe de liaison et (b) un agent thérapeutique renfermant un groupe de liaison qui se lie au premier groupe de liaison par une liaison non covalente à température ambiante.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)