WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2006081000) (POLYALKOXY)SULFONATE SURFACE MODIFIERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/081000    International Application No.:    PCT/US2005/045321
Publication Date: 03.08.2006 International Filing Date: 15.12.2005
IPC:
C08G 65/326 (2006.01), C08G 65/334 (2006.01), C08L 71/02 (2006.01)
Applicants: BAXTER INTERNATIONAL INC. [US/US]; One Baxter Parkway, Deerfield, Illinois 60015 (US) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
BAXTER HEALTHCARE S.A. [CH/CH]; HERTISTRASSE 2, Ch-8306 Wallisellen Kanton, Zurich (CH) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
KIPP, James E. [US/US]; (US) (For US Only).
HAI, Ton That [US/US]; (US) (For US Only).
MELNICK, Bennett, P. [US/US]; (US) (For US Only)
Inventors: KIPP, James E.; (US).
HAI, Ton That; (US).
MELNICK, Bennett, P.; (US)
Agent: MAYO, Michael C.; Baxter International Inc., One Baxter Parkway, Deerfield, US 60015 (US)
Priority Data:
60/638,067 21.12.2004 US
Title (EN) (POLYALKOXY)SULFONATE SURFACE MODIFIERS
(FR) MODIFICATEURS DE SURFACE DE (POLYALCOXY)SULFONATE
Abstract: front page image
(EN) The present invention is directed to novel compounds, methods of manufacture and methods of use. The present invention is also directed to solid drug/active agent particles having one or more of the compounds of the present invention associated with the surface thereof. The compounds of the present invention are comprised of a non-polar polyether covalently linked to an anionic sulfonate group. The compounds have an amphipathic quality and preferably, are surface active. Such compounds are preferably useful as surface-active agents to coat and stabilize dispersions of particles in a continuous liquid medium. These surface-active agents may be applied in the stabilization of suspensions, emulsions, or liposome formulations intended for pharmaceutical, medical, cosmetic, or agricultural use. The particles that can be prepared by a variety of methods and will preferably comprise a pharmaceutical agent. Pharmaceutical compositions of the present invention can be used to treat amyriad of conditions and can be administered by many routes, including intravenous, intramuscular, subcutaneous, intrathecal, subdural, intracameral, intracerebral, intralesional, topical, oral, buccal, rectal, pulmonary, and nasal.
(FR)L'invention concerne des nouveaux composés, des procédés de production et d'utilisation associés. L'invention concerne également des particules de médicament/d'agent actif solides sur la surface desquelles sont associés un ou plusieurs desdits composés. Les composés de l'invention comprennent un polyéther non polaire lié par covalence à un groupe sulfonate anionique. Lesdits composés présentent une qualité amphipathique et sont de préférence tensioactifs. Lesdits composés sont de préférence utiles en tant qu'agents tensioactifs pour revêtir et stabiliser des dispersions de particules dans un milieu liquide continu. Ces agents tensioactifs peuvent être utilisés dans la stabilisation de suspensions, d'émulsions, ou de formulations de liposomes utilisées à des fins pharmaceutiques, médicales, cosmétiques, ou agricoles. Les particules de l'invention peuvent être préparées selon divers procédés et comprennent de préférence un agent pharmaceutique. Les compositions pharmaceutiques de l'invention peuvent être utilisées pour traiter plusieurs états et peuvent être administrées par des voies diverses, de type intraveineuse, intramusculaire, sous-cutanée, intrathécale, sous-durale, intracamérulaire, intracérébrale, intralésionnelle, topique, orale, buccale, rectale, pulmonaire, et nasale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)