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1. (WO2006080022) MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/080022    International Application No.:    PCT/IL2006/000124
Publication Date: 03.08.2006 International Filing Date: 31.01.2006
IPC:
A61K 31/555 (2006.01)
Applicants: YEDA RESEARCH AND DEVELOPMENT CO. LTD. [IL/IL]; At The Weizmann Institute Of Science, P.O. Box 95, 76100 Rehovot (IL) (For All Designated States Except US).
DEGANI, Hadassa [IL/IL]; (IL) (For US Only).
MILSTEIN, David [IL/IL]; (IL) (For US Only)
Inventors: DEGANI, Hadassa; (IL).
MILSTEIN, David; (IL)
Agent: BEN-AMI, Paulina; Ben-Ami & Associates, P.O. Box 94, 76100 Rehovot (IL)
Priority Data:
60/647,821 31.01.2005 US
Title (EN) MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS
(FR) AGENTS DE CONTRASTE IRM POUR DIAGNOSTIC ET PRONOSTIC DE TUMEURS
Abstract: front page image
(EN)The invention relates to bifunctional conjugates comprising a receptor ligand moiety and a metal binding moiety and complexes thereof with paramagnetic lanthanide or transition metals, and to the use of the metal complexes as contrast agents in magnetic resonance imaging (MRI) of tumors and other abnormalities.
(FR)La présente invention concerne des conjugués bifonctionnels comprenant une fraction de ligand de récepteur et une fraction de liaison métallique et des complexes de ces fractions avec un lanthanide paramagnétique ou des métaux de transition et, l'utilisation de ces complexes métalliques comme agents de contraste dans l'imagerie par résonance magnétique (IRM) de tumeurs et d'autres de anomalies.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)