Processing

Please wait...

Settings

Settings

Goto Application

1. WO2006067423 - GLYCINE TRANSPORT INHIBITORS

Publication Number WO/2006/067423
Publication Date 29.06.2006
International Application No. PCT/GB2005/004951
International Filing Date 21.12.2005
Chapter 2 Demand Filed 01.08.2006
IPC
C07C 233/78 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
233Carboxylic acid amides
64having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
77having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
78with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
A61K 31/166 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
166having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
C07C 211/36 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
211Compounds containing amino groups bound to a carbon skeleton
33having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
34of a saturated carbon skeleton
36containing at least two amino groups bound to the carbon skeleton
CPC
A61K 31/166
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
166having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
C07C 211/36
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
211Compounds containing amino groups bound to a carbon skeleton
33having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
34of a saturated carbon skeleton
36containing at least two amino groups bound to the carbon skeleton
C07C 233/77
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
233Carboxylic acid amides
64having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
77having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
Applicants
  • GLAXO GROUP LIMITED [GB]/[GB] (AllExceptUS)
  • BRADLEY, Daniel, Marcus [GB]/[GB] (UsOnly)
  • BRANCH, Clive, Leslie [GB]/[GB] (UsOnly)
  • CHAN, Wai, Ngor [GB]/[GB] (UsOnly)
  • COULTON, Steven [GB]/[GB] (UsOnly)
  • GILPIN, Martin, Leonard [GB]/[GB] (UsOnly)
  • HARRIS, Andrew, Jonathan [GB]/[GB] (UsOnly)
  • JAXA-CHAMIEC, Albert, Andrzej [GB]/[GB] (UsOnly)
  • LAI, Justine, Yeun, Quai [SG]/[GB] (UsOnly)
  • MARSHALL, Howard, Robert [GB]/[GB] (UsOnly)
  • MACRITCHIE, Jacqueline, Anne [GB]/[GB] (UsOnly)
  • NASH, David, John [GB]/[GB] (UsOnly)
  • PORTER, Roderick, Alan [GB]/[GB] (UsOnly)
  • SPADA, Simone [IT]/[IT] (UsOnly)
  • THEWLIS, Kevin, Michael [GB]/[GB] (UsOnly)
  • WARD, Simon, Edward [GB]/[GB] (UsOnly)
Inventors
  • BRADLEY, Daniel, Marcus
  • BRANCH, Clive, Leslie
  • CHAN, Wai, Ngor
  • COULTON, Steven
  • GILPIN, Martin, Leonard
  • HARRIS, Andrew, Jonathan
  • JAXA-CHAMIEC, Albert, Andrzej
  • LAI, Justine, Yeun, Quai
  • MARSHALL, Howard, Robert
  • MACRITCHIE, Jacqueline, Anne
  • NASH, David, John
  • PORTER, Roderick, Alan
  • SPADA, Simone
  • THEWLIS, Kevin, Michael
  • WARD, Simon, Edward
Agents
  • CONNELL, Anthony, Christopher
Priority Data
0428231.523.12.2004GB
0509204.405.05.2005GB
0524320.929.11.2005GB
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) GLYCINE TRANSPORT INHIBITORS
(FR) INHIBITEURS DE TRANSPORT DE LA GLYCINE
Abstract
(EN) The present invention relates to compounds of formula (I), or to salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
(FR) La présente invention concerne des composés de formule (I), ou des sels ou solvates desdits composés, ainsi que leur emploi dans la fabrication de médicaments destinés au traitement de troubles neurologiques et neuropsychiatriques, en particulier les troubles tels que les psychoses, la démence ou le déficit d'attention. La présente invention décrit en outre des procédés permettant d'élaborer ces composés ainsi que les formules pharmaceutiques correspondantes.
Related patent documents
PH12007501298This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
CO7062883This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
DZDZP2007000457This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
NO20073300This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
Latest bibliographic data on file with the International Bureau