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1. WO2006052950 - 5,6,7-TRIHYDROXYHEPTANOIC ACID AND ANALOGS FOR THE TREATMENT OF OCULAR DISEASES AND DISEASES ASSOCIATED WITH HYPERPROLIFERATIVE AND ANGIOGENIC RESPONSES

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Publication Number WO/2006/052950
Publication Date 18.05.2006
International Application No. PCT/US2005/040392
International Filing Date 08.11.2005
Chapter 2 Demand Filed 18.08.2006
IPC
A61K 31/047 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
047having two or more hydroxy groups, e.g. sorbitol
A61P 27/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
CPC
A61K 31/047
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
047having two or more hydroxy groups, e.g. sorbitol
A61K 31/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
20having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
A61K 31/22
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
A61K 31/366
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
365Lactones
366having six-membered rings, e.g. delta-lactones
A61K 9/0048
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0048Eye, e.g. artificial tears
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
Applicants
  • ALCON, INC. [CH]/[CH] (AllExceptUS)
  • KLIMKO, Peter, G. [US]/[US] (UsOnly)
  • HELLBERG, Mark, R. [US]/[US] (UsOnly)
  • BINGAMAN, David, P. [US]/[US] (UsOnly)
  • GAMACHE, Daniel, A. [US]/[US] (UsOnly)
Inventors
  • KLIMKO, Peter, G.
  • HELLBERG, Mark, R.
  • BINGAMAN, David, P.
  • GAMACHE, Daniel, A.
Agents
  • SCHULTZ, Teresa, J.
Priority Data
60/626,20909.11.2004US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) 5,6,7-TRIHYDROXYHEPTANOIC ACID AND ANALOGS FOR THE TREATMENT OF OCULAR DISEASES AND DISEASES ASSOCIATED WITH HYPERPROLIFERATIVE AND ANGIOGENIC RESPONSES
(FR) ACIDE 5,6,7-TRIHYDROXYHEPTANOIQUE ET ANALOGUES DUDIT ACIDE DANS LE TRAITEMENT DE MALADIES OCULAIRES OU ASSOCIEES A DES REACTIONS DE TYPE HYPERPROLIFERANTES ET ANGIOGENIQUES
Abstract
(EN) Compositions containing 5,6,7-trihydroxyheptanoic acid and analogs and their use for treating posterior segment ocular diseases and diseses characterized by cellular hyperproliferation or angiogenesis, are disclosed.
(FR) La présente invention a pour objet des préparations contenant l’acide 5,6,7-trihydroxyheptanoïque ou l’un de ses analogues, et l’utilisation desdites préparations dans le traitement des maladies du segment postérieur de l’œil, ainsi que des maladies caractérisées par une hyperprolifération cellulaire ou de l’angiogenèse.
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