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1. WO2006046814 - SOPHORAE SUBPROSTRATAE RADIX EXTRACT FOR PREVENTION AND TREATMENT OF RESPIRATORY DISEASES

Publication Number WO/2006/046814
Publication Date 04.05.2006
International Application No. PCT/KR2005/003522
International Filing Date 21.10.2005
Chapter 2 Demand Filed 04.04.2006
IPC
A61K 36/489 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
489Sophora, e.g. necklacepod or mamani
A61P 11/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
CPC
A61K 2236/33
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2236Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
30Extraction of the material
33involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
A61K 36/489
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
489Sophora, e.g. necklacepod or mamani
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
02Nasal agents, e.g. decongestants
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Applicants
  • SK CHEMICALS, CO., LTD. [KR]/[KR] (AllExceptUS)
  • HAN, Chang-Kyun [KR]/[KR] (UsOnly)
  • JOUNG, Kiwon [KR]/[KR] (UsOnly)
  • YOO, Hunseung [KR]/[KR] (UsOnly)
  • CHO, Yong-Baik [KR]/[KR] (UsOnly)
  • RYU, Keun Ho [KR]/[KR] (UsOnly)
  • BAEK, Hye Yeon [KR]/[KR] (UsOnly)
  • KIM, Taek-Soo [KR]/[KR] (UsOnly)
  • JUNG, In Ho [KR]/[KR] (UsOnly)
  • KWAK, Wie-Jong [KR]/[KR] (UsOnly)
Inventors
  • HAN, Chang-Kyun
  • JOUNG, Kiwon
  • YOO, Hunseung
  • CHO, Yong-Baik
  • RYU, Keun Ho
  • BAEK, Hye Yeon
  • KIM, Taek-Soo
  • JUNG, In Ho
  • KWAK, Wie-Jong
Agents
  • PAIK, Nam-Hoon
Priority Data
10-2004-008628227.10.2004KR
Publication Language English (en)
Filing Language Korean (KO)
Designated States
Title
(EN) SOPHORAE SUBPROSTRATAE RADIX EXTRACT FOR PREVENTION AND TREATMENT OF RESPIRATORY DISEASES
(FR) EXTRAIT DE SOPHORAE SUBSPROSTRATAE RADIX POUR LA PREVENTION ET LE TRAITEMENT DE MALADIES RESPIRATOIRES
Abstract
(EN) The present invention relates to an extract isolated from Sophorae Radix useful for prevention and treatment of respiratory diseases. More specifically, the present invention relates to a pharmaceutical drug comprising the Sophorae Radix extract having excellent effects of inhibiting airway contraction, respiratory infections, 5-lipoxygenase activity, phosphodiesterase 4 activity, airway hyper-responsiveness and airway remodeling; antagonistic activity against leukotriene D4; and an antitussive effect, thus being useful for prevention and treatment of respiratory diseases such as asthma, acute or chronic bronchitis, allergic rhinitis, acute upper respiratory infections and acute lower respiratory infections, and the like.
(FR) La présente invention se rapporte à un extrait isolé de Sophorae subprostratae Radix utile pour la prévention et le traitement de maladies respiratoires. Plus spécifiquement, la présente invention se rapporte à un médicament pharmaceutique comprenant l'extrait de Sophorae subprostratae Radix et présentant d'excellents effets d'inhibition de la contraction des voies aériennes, des infections respiratoires, de l'activité 5-lipoxygénase, de l'activité phosphodiestérase 4, de l'hyperréactivité des voies aériennes et du remodelage des voies aériennes; de l'activité antagoniste dirigée contre du leucotriène D4; ainsi qu'un effet antitussif, ledit médicament s'avérant par conséquent utile pour la prévention et le traitement des maladies respiratoires telles que l'asthme, la bronchite aiguë ou chronique, la rhinite allergique, les infections respiratoires supérieures aiguës et les infections respiratoires inférieures aiguës, et analogues.
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