Processing

Please wait...

Settings

Settings

Goto Application

1. WO2006041967 - METHOD OF FORMATION OF THE SHAPE-RETENTIVE AGGREGATES OF GEL PARTICLES AND THEIR USES

Publication Number WO/2006/041967
Publication Date 20.04.2006
International Application No. PCT/US2005/035905
International Filing Date 06.10.2005
IPC
A61K 9/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
CPC
A61K 9/0024
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
A61K 9/1635
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
16Agglomerates; Granulates; Microbeadlets ; ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
1605Excipients; Inactive ingredients
1629Organic macromolecular compounds
1635obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
A61K 9/5138
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51Nanocapsules; Nanoparticles;
5107Excipients; Inactive ingredients
513Organic macromolecular compounds; Dendrimers
5138obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
A61K 9/5192
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51Nanocapsules; Nanoparticles;
5192Processes
A61L 2300/252
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
20containing or releasing organic materials
252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
A61L 2300/406
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
40characterised by a specific therapeutic activity or mode of action
404Biocides, antimicrobial agents, antiseptic agents
406Antibiotics
Applicants
  • ULURU INC. [US]/[US] (AllExceptUS)
  • MORO, Daniel, G. [US]/[US] (UsOnly)
  • ST.JOHNN, John, V. [US]/[US] (UsOnly)
  • SHANNON, Kevin, F. [US]/[US] (UsOnly)
  • PONDER, Bill, C. [US]/[US] (UsOnly)
Inventors
  • MORO, Daniel, G.
  • ST.JOHNN, John, V.
  • SHANNON, Kevin, F.
  • PONDER, Bill, C.
Agents
  • KONSKI, Antoinette, F.
Priority Data
10/960,46106.10.2004US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF FORMATION OF THE SHAPE-RETENTIVE AGGREGATES OF GEL PARTICLES AND THEIR USES
(FR) PROCEDE DE FORMATION D'AGREGATS DE PARTICULES DE GEL A MEMOIRE DE FORME ET UTILISATIONS ASSOCIEES
Abstract
(EN)
The present invention relates to a method of forming shape-retentive aggregates of gel particles in which the aggregates are held together by non­ covalent bond physical forces such as, without limitation, hydrophobic­hydrophilic interactions and hydrogen bonds. The method comprises introducing a suspension of gel particles in a polar liquid at a selected concentration, wherein the gel particles have an absolute zeta potential, into a medium in which the absolute zeta potential of the gel particles is decreased, resulting in the gel particles coalescing into the claimed shape-retentive aggregate. This invention also relates to uses of the method of formation of the shape-retentive aggregates of gel particles.
(FR)
L'invention concerne un procédé de formation d'agrégats de particules de gel à mémoire de forme, ces agrégats étant maintenus ensemble par des forces physiques de liaisons non covalentes telles que, entre autres, des interactions hydrophobes-hydrophiles et des liaisons hydrogène. Ce procédé consiste à introduire une suspension de particules de gel dans un liquide polaire, dans une concentration déterminée, les particules de gel présentant un potentiel zêta absolu, dans un milieu dans lequel le potentiel zêta absolu des particules de gel est réduit, ce qui entraîne la coalescence des particules de gel et produit l'agrégat à mémoire de forme selon l'invention. L'invention concerne également les utilisations de ce procédé de formation d'agrégats de particules de gel à mémoire de forme.
Latest bibliographic data on file with the International Bureau