Processing

Please wait...

PATENTSCOPE will be unavailable a few hours for maintenance reason on Tuesday 26.10.2021 at 12:00 PM CEST
Settings

Settings

Goto Application

1. WO2006041945 - A COUNTERION EXCHANGE PROCESS FOR PEPTIDES

Publication Number WO/2006/041945
Publication Date 20.04.2006
International Application No. PCT/US2005/035868
International Filing Date 04.10.2005
IPC
C07K 1/20 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General processes for the preparation of peptides
14Extraction; Separation; Purification
16by chromatography
20Partition-, reverse-phase or hydrophobic interaction chromatography
C07K 7/16 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
16Oxytocins; Vasopressins; Related peptides
C07K 14/655 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
655Somatostatins
C07K 14/585 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
585Calcitonins
C07K 14/575 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
CPC
C07K 1/20
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General methods for the preparation of peptides ; , i.e. processes for the organic chemical preparation of peptides or proteins of any length
14Extraction; Separation; Purification
16by chromatography
20Partition-, reverse-phase or hydrophobic interaction chromatography
C07K 14/575
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
C07K 7/16
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
16Oxytocins; Vasopressins; Related peptides
Applicants
  • NOVETIDE, LTD. [IL]/[IL] (AE, AG, AL, AM, AT, AU, AZ, BA, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW)
  • TEVA PHARMACEUTICALS USA, INC. [US]/[US] (BB)
  • TOVI, Avi [IL]/[IL] (UsOnly)
  • EIDELMAN, Chaim [IL]/[IL] (UsOnly)
  • SHUSHAN, Shimon [IL]/[IL] (UsOnly)
  • ELSTER, Shai [IL]/[IL] (UsOnly)
  • ALON, Hagi [IL]/[IL] (UsOnly)
  • IVCHENKO, Alexander [IL]/[IL] (UsOnly)
  • BUTILCA, Gabriel-Marcus [IL]/[IL] (UsOnly)
  • ZAOVI, Gil [IL]/[IL] (UsOnly)
Inventors
  • TOVI, Avi
  • EIDELMAN, Chaim
  • SHUSHAN, Shimon
  • ELSTER, Shai
  • ALON, Hagi
  • IVCHENKO, Alexander
  • BUTILCA, Gabriel-Marcus
  • ZAOVI, Gil
Agents
  • BRAINARD, Charles, R.
Priority Data
60/616,01004.10.2004US
60/630,52822.11.2004US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A COUNTERION EXCHANGE PROCESS FOR PEPTIDES
(FR) PROCESSUS D'ECHANGE DE CONTRE-ION POUR PEPTIDES
Abstract
(EN)
The invention encompasses a process for purifying a peptide comprising loading a peptide onto a RP-HPLC column; washing the column with an aqueous solution of a pharmaceutically acceptable counterion salt; and eluting the peptide from the column with a solvent mixture of a organic solvent and an acid of the pharmaceutically acceptable counterion, wherein the aqueous solution has a pH of at least about 6.
(FR)
La présente invention concerne un processus de purification de peptide qui consiste à charger un peptide sur une colonne, à laver cette colonne avec une solution aqueuse d'un sel de contre-ion répondant aux normes pharmaceutiques et, à éluer le peptides de la colonne avec un mélange solvant d'un solvant organique et d'un acide de ce contre-ion répondant aux normes pharmaceutiques, cette solution aqueuse possédant un pH d'au moins six.
Latest bibliographic data on file with the International Bureau