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1. (WO2006031134) ANTI-INFLAMMATORY COMPOUNDS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2006/031134 International Application No.: PCT/NZ2005/000246
Publication Date: 23.03.2006 International Filing Date: 16.09.2005
Chapter 2 Demand Filed: 13.04.2006
IPC:
C07D 513/04 (2006.01) ,C07D 279/16 (2006.01) ,A61K 31/542 (2006.01) ,A61K 31/5415 (2006.01) ,A61P 29/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
513
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/, C07D477/232
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
279
Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
10
1,4-Thiazines; Hydrogenated 1,4-thiazines
14
condensed with carbocyclic rings or ring systems
16
condensed with one six-membered ring
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
54
having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame
542
ortho- or peri-condensed with heterocyclic ring systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
54
having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame
5415
ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
Applicants:
NEW ZEALAND INSTITUTE FOR CROP & FOOD RESEARCH LIMITED [NZ/NZ]; C/- C A N T Agriculture & Science Centre Gerald Street Lincoln, NZ (AllExceptUS)
NATIONAL INSTITUTE OF WATER AND ATMOSPHERIC RESEARCH LIMITED [NZ/NZ]; 269 Khyber Pass Road Newmarket Auckland, NZ (AllExceptUS)
THE MALAGHAN INSTITUTE OF MEDICAL RESEARCH [NZ/NZ]; CSB Building Entrance 7 Kelburn Parade Wellington, NZ (AllExceptUS)
DENNY, William Alexander [NZ/NZ]; NZ (UsOnly)
COPP, Brent Raymond [NZ/NZ]; NZ (UsOnly)
PEARCE, Allison Norrie [NZ/NZ]; NZ (UsOnly)
BERRIDGE, Michael Vivian [NZ/NZ]; NZ (UsOnly)
HARPER, Jacquie Lucille [NZ/NZ]; NZ (UsOnly)
PERRY, Nigel Brian [NZ/NZ]; NZ (UsOnly)
LARSEN, Lesley [NZ/NZ]; NZ (UsOnly)
GODFREY, Colette Amirah [AU/AU]; AU (UsOnly)
Inventors:
DENNY, William Alexander; NZ
COPP, Brent Raymond; NZ
PEARCE, Allison Norrie; NZ
BERRIDGE, Michael Vivian; NZ
HARPER, Jacquie Lucille; NZ
PERRY, Nigel Brian; NZ
LARSEN, Lesley; NZ
GODFREY, Colette Amirah; AU
Agent:
BALDWINS; P O Box 852 Wellington, NZ
Priority Data:
53538317.09.2004NZ
Title (EN) ANTI-INFLAMMATORY COMPOUNDS
(FR) COMPOSES ANTI-INFLAMMATOIRES
Abstract:
(EN) The invention relates to compounds of formula (I) or formula (II) which have anti-inflammatory activity and comprise a new class of NSAIDs. The compounds are therefore useful for treating inflammatory diseases or disorders. The invention also relates to pharmaceutical compositions containing these compounds, as well as methods of treating inflammatory diseases or disorders using compounds of formula (III) or formula (IV).
(FR) L'invention concerne des composés représentés par la formule (I) ou la formule (II) possédant une activité anti-inflammatoire et comprenant une nouvelle classe de NSAIDs. Lesdits composés sont ainsi utilisés dans le traitement de maladies ou de troubles inflammatoires. L'invention concerne également des compositions pharmaceutiques contenant lesdits composés, ainsi que des méthodes de traitement des maladies ou des troubles inflammatoires à l'aides desdits composés représentés par la formule (III) ou la formule (IV).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1789422US20070265253CA2580496AU2005285546