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1. (WO2006020824) DIAGNOSIS AND TREATMENT OF KAWASAKI DISEASE AND CORONAVIRUS INFECTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/020824    International Application No.:    PCT/US2005/028664
Publication Date: 23.02.2006 International Filing Date: 11.08.2005
IPC:
C12Q 1/68 (2006.01)
Applicants: YALE UNIVERSITY [US/US]; Two Whitney Avenue, New Haven, CT 06511 (US) (For All Designated States Except US).
KAHN, Jeffrey, S. [US/US]; (US) (For US Only).
ESPER, Frank [US/US]; (US) (For US Only)
Inventors: KAHN, Jeffrey, S.; (US).
ESPER, Frank; (US)
Agent: GRANAHAN, Patricia; Wolf, Greenfield & Sacks, P.C., 600 Atlantic Avenue, Boston, MA 02210-2206 (US)
Priority Data:
60/601,036 11.08.2004 US
Title (EN) DIAGNOSIS AND TREATMENT OF KAWASAKI DISEASE AND CORONAVIRUS INFECTION
(FR) DIAGNOSTIC ET TRAITEMENT DE LA MALADIE DE KAWASAKI ET D'UNE INFECTION A CORONAVIRUS
Abstract: front page image
(EN)In certain embodiments, the present invention relates to a novel coronavirus designed HCoV-NH. Also disclosed are isolated HCoV-NH nucleic acids, proteins encoded by the HCoV-NH nucleic acids, related expression vectors, related host cells, related antibodies, and related compositions. Methods of diagnosing infection with a coronavirus, methods of diagnosing Kawasaki disease, methods of identifying a therapeutic compound, and methods for treating coronavirus infection and for treating Kawasaki disease are also disclosed.
(FR)Dans certains modes de réalisation, l'invention a trait à un nouveau coronavirus dénommé HCoV-NH. L'invention concerne également des acides nucléiques du HCoV-NH, des protéines encodées par les acides nucléiques du HCoV-NH, des vecteurs d'expression associés, des cellules hôtes associées, des anticorps associés et des compositions associées. L'invention se rapporte également à des méthodes permettant de diagnostiquer une infection à coronavirus, à des méthodes permettant de diagnostiquer la maladie de Kawasaki, à des méthodes permettant d'identifier un composé thérapeutique, et à des méthodes permettant de traiter une infection à coronavirus et la maladie de Kawasaki.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)