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1. (WO2006020681) COMPOUNDS AND METHODS FOR THE TREATMENT OF UBIQUITIN CONJUGATING DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/020681    International Application No.:    PCT/US2005/028358
Publication Date: 23.02.2006 International Filing Date: 10.08.2005
IPC:
A01N 37/18 (2006.01)
Applicants: HYGEIA BIOLOGICAL SYSTEMS [US/US]; 5200 Anthony Wayne Drive, Detroit, MI 48202 (US) (For All Designated States Except US).
BANERJEE, Amit [IN/US]; (US) (For US Only)
Inventors: BANERJEE, Amit; (US)
Agent: WILLIAMS, Kathleen, M.; Edwards Angell Palmer & Dodge LLP, 111 Huntington Avenue, Boston, MA 02199-7613 (US)
Priority Data:
10/914,848 10.08.2004 US
Title (EN) COMPOUNDS AND METHODS FOR THE TREATMENT OF UBIQUITIN CONJUGATING DISORDERS
(FR) COMPOSES ET PROCEDES DESTINES AU TRAITEMENT DES TROUBLES DE CONJUGAISON D'UBIQUITINE
Abstract: front page image
(EN)The present invention provides methods for identifying compounds that selectively bind one or more active sites within an ubiquitin conjugating enzyme. The compounds identified by the methods are useful in the treatment of disorders attributed to dysregulated ubiquitin conjugating enzyme function, specifically in hyperproliferative disorders.
(FR)La présente invention concerne des procédés pour identifier des composés qui lient sélectivement un ou plusieurs sites actifs à l'intérieur d'une enzyme de conjugaison d'ubiquitine. Les composés identifiés par les procédés de l'invention sont utiles dans le traitement des troubles attribués à la fonction d'enzyme de conjugaison d'ubiquitine, et plus particulièrement des troubles hyperprolifératifs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)