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1. (WO2006019982) PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/019982    International Application No.:    PCT/US2005/025097
Publication Date: 23.02.2006 International Filing Date: 15.07.2005
IPC:
A61K 38/00 (2006.01), A61K 38/02 (2006.01), A61K 38/06 (2006.01), A61K 38/07 (2006.01), A61K 38/08 (2006.01), C07K 2/00 (2006.01), C07K 5/02 (2006.01), C07K 7/04 (2006.01), C07K 5/10 (2006.01)
Applicants: VERNALIS PLC [GB/GB]; Oakdene Court, Winnersh, Berkshire RG41 5UA (GB) (For All Designated States Except US).
BETH ISRAEL DEACONESS MEDICAL CENTER [US/US]; 330 Brookline Avenue, Boston, MA 02215 (US) (For All Designated States Except US).
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES [US/US]; 10010 North Torrey Pines Road, La Jolla, CA 92037 (US) (For All Designated States Except US).
LU, Kun, Ping [US/US]; (US) (For US Only).
SUTO, Robert, K. [US/US]; (US) (For US Only).
SOWADSKI, Janusz, M. [US/US]; (US) (For US Only).
FISCHER, Gunter, S. [DE/DE]; (DE) (For US Only).
NOEL, Joseph, P. [US/US]; (US) (For US Only).
VERDECIA, Mark [US/US]; (US) (For US Only)
Inventors: LU, Kun, Ping; (US).
SUTO, Robert, K.; (US).
SOWADSKI, Janusz, M.; (US).
FISCHER, Gunter, S.; (DE).
NOEL, Joseph, P.; (US).
VERDECIA, Mark; (US)
Agent: HANLEY, Elizabeth, A.; Lahive & Cockfield, LLP, One Post Office Square, Boston, MA 02109-2127 (US)
Priority Data:
60/588,421 15.07.2004 US
Title (EN) PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF
(FR) COMPOSES MODULATEURS DE PIN1 ET LEURS PROCEDES D'UTILISATION
Abstract: front page image
(EN)The invention is directed to peptide modulators of Pin1 and Pin1-related proteins and the use of such modulators for treatment of Pin1 associated states, e.g., for the treatment of cancer or neurodegenerative disease.
(FR)La présente invention a trait à des modulateurs peptidiques de protéines associées à Pin1 et à Pin2 et l'utilisation de tels modulateurs pour le traitement d'états associés à Pin1, tel que le traitement du cancer et de maladie neurodégénérative.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)