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1. (WO2006019118) METHOD OF JUDGING RISK OF DECAY AND JUDGMENT REAGENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/019118    International Application No.:    PCT/JP2005/015017
Publication Date: 23.02.2006 International Filing Date: 17.08.2005
IPC:
G01N 33/573 (2006.01), G01N 33/50 (2006.01), G01N 33/577 (2006.01), C07K 16/40 (2006.01), C12Q 1/48 (2006.01)
Applicants: NIHON UNIVERSITY [JP/JP]; 8-24, Kudan-minami 4-chome, Chiyoda-ku, Tokyo 1028275 (JP) (For All Designated States Except US).
DAIICHI PURE CHEMICALS CO., LTD. [JP/JP]; 13-5, Nihonbashi 3-chome, Chuo-ku, Tokyo 1030027 (JP) (For All Designated States Except US).
FUKUSHIMA, Kazuo [JP/JP]; (JP) (For US Only).
KOBORI, Kiichiro [JP/JP]; (JP) (For US Only).
USHIZAWA, Koji [JP/JP]; (JP) (For US Only)
Inventors: FUKUSHIMA, Kazuo; (JP).
KOBORI, Kiichiro; (JP).
USHIZAWA, Koji; (JP)
Agent: THE PATENT CORPORATE BODY ARUGA PATENT OFFICE; Kyodo Bldg. 3-6, Nihonbashiningyocho 1-chome Chuo-ku, Tokyo 1030013 (JP)
Priority Data:
2004-237903 18.08.2004 JP
Title (EN) METHOD OF JUDGING RISK OF DECAY AND JUDGMENT REAGENT
(FR) PROCEDE PERMETTANT D'EVALUER LE RISQUE DE CARIES ET REACTIF ASSOCIE
(JA) う蝕リスクの判定方法及び判定薬
Abstract: front page image
(EN)It is intended to provide a method of conveniently and quickly judging the onset level and risk of decay and a judgment reagent therefor. Namely, a method of judging the risk of decay characterized by using a reagent containing a monoclonal antibody against GTF-I originating in Streptococcus sobrinus and quantifying the GTF-I in the oral cavity; and a reagent for judging the risk of decay which contains a monoclonal antibody against GTF-I originating in Streptococcus sobrinus and another monoclonal antibody against GTF-B originating in Streptococcus mutans
(FR)L'invention concerne un procédé permettant de déterminer rapidement et efficacement l'apparition et le risque de caries, ainsi qu'un réactif associé. L'invention concerne en particulier un procédé permettant d'évaluer le risque de caries. Ce procédé se caractérise en ce qu'il consiste à utiliser un réactif contenant un anticorps monoclonal contre GTF-I issu de Streptococcus sobrinus, et à quantifier le GTF-I dans la cavité buccale. L'invention concerne également un réactif servant à évaluer le risque de caries, ledit réactif contenant un anticorps monoclonal contre GTF-I issu de Streptococcus sobrinus et un autre anticorps monoclonal contre GTF-B issu de Streptococcus mutans.
(JA) う蝕の発生程度や発生の危険性を簡便かつ迅速に判定するための方法及び判定薬を提供する。  本発明は、ストレプトコッカス・ソブリヌス由来のGTF-Iに対するモノクローナル抗体を含有する試薬を用いて口腔内の当該GTF-I量を測定することを特徴とするう蝕リスクの判定方法、並びにストレプトコッカス・ソブリヌス由来のGTF-Iに対するモノクローナル抗体及びストレプトコッカス・ミュータンス由来のGTF-Bに対するモノクローナル抗体を含有するう蝕リスクの判定薬。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)