Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2006017816) PRODUCT AND PROCESS FOR INHIBITION OF BIOFILM DEVELOPMENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2006/017816 International Application No.: PCT/US2005/028076
Publication Date: 16.02.2006 International Filing Date: 04.08.2005
IPC:
A61K 39/00 (2006.01) ,A61K 31/70 (2006.01) ,A01N 43/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43
Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
02
having rings with one or more oxygen or sulfur atoms as the only ring hetero atom
04
with one hetero atom
Applicants:
NATIONAL JEWISH MEDICAL AND RESEARCH CENTER [US/US]; 1400 Jackson Street Denver, CO 80206, US (AllExceptUS)
NICK, Jerry, A. [US/US]; US (UsOnly)
WALKER, Travis, S. [US/US]; US (UsOnly)
WORTHEN, Scott, G. [US/US]; US (UsOnly)
Inventors:
NICK, Jerry, A.; US
WALKER, Travis, S.; US
WORTHEN, Scott, G.; US
Agent:
SEBOR, Angela, Dallas ; Sheridan Ross P.C. 1560 Broadway, Suite 1200 Denver, CO 80202-5141, US
Priority Data:
60/599,49506.08.2004US
Title (EN) PRODUCT AND PROCESS FOR INHIBITION OF BIOFILM DEVELOPMENT
(FR) PRODUIT ET PROCEDE PERMETTANT D'EMPECHER LE DEVELOPPEMENT D'UN FILM BIOLOGIQUE
Abstract:
(EN) Disclosed are compositions and methods for the inhibition of biofilm formation or reduction of existing or developing biofilms in a patient. These methods also inhibit the aggregation of bacteria that form biofilms in the airways. The methods include administering to a subject that has or is at risk of developing biofilms a compound or formulation that inhibits the formation or polymerization of actin microfilaments or depolymerizes actin microfilaments at or proximal to the site of biofilm formation. Such a compound can be administered in combination with a compound or formulation that inhibits the accumulation or activity of cells that are likely to undergo necrosis at or proximal to the site of biofilm formation (i.e., neutrophils). The methods and compositions can further include the use of anti-DNA and/or anti-mucin compounds, as well as other therapeutic compounds and compositions.
(FR) L'invention concerne des compositions et des méthodes permettant d'empêcher la formation d'un film biologique ou de réduire les films biologiques existants ou en formation chez un patient. Ce méthodes empêchent en outre l'agrégation des bactéries formant un film biologique dans les voies respiratoires. Les méthodes décrites consistent à administrer à un sujet présentant des films biologiques ou risquant l'apparition de ces derniers un composé ou une préparation qui inhibe la formation ou la polymérisation des microfilaments d'actine, ou dépolymérise les microfilaments d'actine, dans le site de formation de film biologique ou à proximité de celui-ci. Ce composé peut être administré en combinaison avec un composé ou une préparation qui inhibe l'accumulation ou l'activité des cellules risquant de subir une nécrose dans le site de formation du film biologique ou à proximité de celui-ci (neutrophiles). Ces méthodes et ces compositions peuvent en outre comprendre l'utilisation de composés anti-ADN et/ou anti-mucine, ainsi que d'autres composés et compositions thérapeutiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1791566CA2578478