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1. (WO2006017169) IMPLANTABLE SENSOR WITH BIOCOMPATIBLE COATING FOR CONTROLLING TISSUE GROWTH
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2006/017169 International Application No.: PCT/US2005/024250
Publication Date: 16.02.2006 International Filing Date: 08.07.2005
IPC:
A61B 5/00 (2006.01) ,A61L 31/10 (2006.01) ,A61L 33/00 (2006.01) ,A61K 9/16 (2006.01) ,A61L 31/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
08
Materials for coatings
10
Macromolecular materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
33
Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
14
Materials characterised by their function or physical properties
16
Biologically active materials, e.g. therapeutic substances
Applicants: CHAVAN, Abhi[US/US]; US (UsOnly)
ROSS, Jeffrey[US/US]; US (UsOnly)
MORRISSEY, Cynthia[US/US]; US (UsOnly)
MAZAR, Scott T.[US/US]; US (UsOnly)
PALME, Donald[US/US]; US (UsOnly)
CARDIAC PACEMAKERS, INC.[US/US]; 4100 Hamline Avenue North St. Paul, MN 55112-5798, US (AllExceptUS)
Inventors: CHAVAN, Abhi; US
ROSS, Jeffrey; US
MORRISSEY, Cynthia; US
MAZAR, Scott T.; US
PALME, Donald; US
Agent: MCCRACKIN, Ann M. ; Schwegman, Lundberg, Woessner & Kluth, P.A. P.O. Box 2938 Minneapolis, MN 55402, US
Priority Data:
10/888,34009.07.2004US
Title (EN) IMPLANTABLE SENSOR WITH BIOCOMPATIBLE COATING FOR CONTROLLING TISSUE GROWTH
(FR) CAPTEUR IMPLANTABLE POURVU D'UN REVETEMENT BIOCOMPATIBLE PERMETTANT DE MAITRISER LA CROISSANCE TISSULAIRE
Abstract:
(EN) [0001] All or a portion of a surface of an implantable sensor is covered with a biocompatible coating formed at least partially of a biomaterial matrix having properties that promote a substantially even growth of tissue cells over the surface of the coating. Additional materials, such as growth factors, agents that recruit endogenous stem cells, and cell adhesion motif arginine, glycine, aspartic acid may be included in the coating. Autologous cells may be added to the coating prior to implantation. The sensor surface may also be textured, by etching or abrading, in order to promote even tissue growth. Alternatively, the sensor surface may be covered with a coating having properties that inhibit the growth of tissue. These coatings may include a biomaterial, a biomaterial matrix having a drug, such as a sirolimus or a steroid, an active component, or a self assembled monolayer.
(FR) Selon la présente invention, on recouvre tout ou partie d'une surface d'un capteur implantable d'un revêtement biocompatible formé au moins partiellement d'une matrice de biomatière possédant des propriétés qui stimulent une croissance sensiblement uniforme de cellules tissulaires par-dessus la surface du revêtement. On peut inclure dans le revêtement, avant l'implantation, des matériaux supplémentaires tels que des facteurs de croissance, des agents de recrutement de cellules souches endogènes, et un motif d'adhésion cellulaire arginine, glycine, acide aspartique. On peut également texturer la surface du capteur par gravure ou abrasion afin de promouvoir davantage la croissance tissulaire. Dans un autre mode de réalisation, on peut recouvrir la surface du capteur d'un revêtement possédant des propriétés qui inhibent la croissance tissulaire. Les revêtements précités peuvent comprendre une biomatière, une matrice de biomatière comprenant un médicament, par exemple le sirolimus ou un stéroïde, un composant actif ou une monocouche autoassemblée.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)