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1. (WO2006017124) OXYGEN/NITROGEN HETEROCYCLE INHIBITORS OF TYROSINE PHOSPHATASES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2006/017124 International Application No.: PCT/US2005/024130
Publication Date: 16.02.2006 International Filing Date: 08.07.2005
IPC:
A61K 31/42 (2006.01)
Applicants: CHERUVALLATH, Zaccharia, S.[US/US]; US (UsOnly)
SEMPLE, Joseph, E.[US/US]; US (UsOnly)
WANG, Jing[CA/US]; US (UsOnly)
NUTT, Ruth, F.[US/US]; US (UsOnly)
MYLVAGANAM, Shankari[GB/US]; US (UsOnly)
CENGENT THERAPEUTICS, INC.[US/US]; 10929 Technology Place San Diego, CA 92127, US (AllExceptUS)
Inventors: CHERUVALLATH, Zaccharia, S.; US
SEMPLE, Joseph, E.; US
WANG, Jing; US
NUTT, Ruth, F.; US
MYLVAGANAM, Shankari; US
Agent: ROTHERY, Brian, M. ; Jones Day 222 East 41st Street New York, NY 10017-6702, US
Priority Data:
60/587,02309.07.2004US
60/634,45008.12.2004US
60/638,56322.12.2004US
Title (EN) OXYGEN/NITROGEN HETEROCYCLE INHIBITORS OF TYROSINE PHOSPHATASES
(FR) INHIBITEURS DE TYROSINE PHOSPHATASES A HETEROCYCLE OXYGENE/AZOTE
Abstract:
(EN) Compounds, pharmaceutical compositions, and methods for treating, preventing, or ameliorating symptoms associated with diseases such as diabetes, cancer, neurodegenerative diseases, and obesity are provided. The compounds and compositions inhibit protein tyrosine phosphatase enzymes, e.g., PTP-1B.
(FR) Dans le cadre de la présente invention des composés, des compositions pharmaceutiques, et des procédés pour traiter, prévenir ou améliorer des symptômes associés à des maladies telles que le diabète, le cancer, les maladies neurodégénératives et l'obésité sont proposés. Les composés et compositions inhibent les enzymes protéine tyrosine phosphatases, par exemple, PTP-1B.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)