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Machine translation
1. (WO2006016807) BIOMIMETIC PROCESS FOR COATING SUBSTRATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/016807    International Application No.:    PCT/NL2005/000580
Publication Date: 16.02.2006 International Filing Date: 10.08.2005
Chapter 2 Demand Filed:    12.06.2006    
IPC:
A61L 27/32 (2006.01), A61L 27/54 (2006.01)
Applicants: YEKIMED AG [CH/CH]; Obermoosstrasse 22, CH-3067 Boll (CH) (For All Designated States Except US).
LIU, Yuelian [NL/NL]; (NL) (For US Only)
Inventors: LIU, Yuelian; (NL)
Agent: VAN WESTENBRUGGE, Andries; Nederlandsch Octrooibureau, P.O. Box 29720, NL-2502 LS The Hague (NL)
Priority Data:
1026814 10.08.2004 NL
Title (EN) BIOMIMETIC PROCESS FOR COATING SUBSTRATES
(FR) PROCEDE BIOMIMETIQUE PERMETTANT DE RECOUVRIR DES SUBSTRATS D'UNE SOLUTION BIOMIMETIQUE CONTENANT UNE SUBSTANCE BIOACTIVE ET UTILISATION DUDIT PROCEDE ET DESDITS SUBSTRATS DANS L'INGENIERIE DES TISSUS OSSEUX, DES TISSUS CONJONCTIFS, DES TISSUX GRAISSEUX ET DES TISSUS MUSCULAIRES
Abstract: front page image
(EN)The invention relates to a biomimetic process for coating a substrate, particularly a medical device, with a biomimetic composition, which comprises: a) producing batchwise in a closed system an acidified biomimetic composition comprising a saline aqueous mixture containing calcium-, magnesium-, phosphate-, bicarbonate ions and a bioactive substance, b) contacting the substrate with said biomimetic composition and c) storing the biomimetic composition in contact with the substrate and allowing a gradual increase of the pH to occur and to cause precipitation of salts and co-precipitation of the bioactive substance on said substrate and to obtain a coated substrate.
(FR)L'invention se rapporte à un procédé biomimétique qui permet de recouvrir un substrat, en particulier d'une composition biomimétique, selon lequel: a) on produit en discontinu dans un système fermé une composition biomimétique acidifiée comprenant un mélange aqueux salin contenant des ions calcium, magnésium, phosphate, bicarbonate et une substance bioactive; b) on met en contact le substrat avec ladite composition biomimétique; et c) on stocke la composition biomimétique en contact avec le substrat en autorisant une augmentation progressive du pH qui entraîne la précipitation des sels et une coprécipitation de la substance bioactive sur ledit substrat, permettant d'obtenir un substrat muni d'un revêtement.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)