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1. (WO2006016705) THE USE OF PHOSPHOKETOLASE FOR PRODUCING USEFUL METABOLITES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/016705    International Application No.:    PCT/JP2005/014966
Publication Date: 16.02.2006 International Filing Date: 10.08.2005
IPC:
C12N 9/88 (2006.01), C12R 1/00 (2006.01), C12P 13/04 (2006.01), C12P 13/10 (2006.01), C12P 13/12 (2006.01), C12P 13/14 (2006.01), C12P 13/24 (2006.01)
Applicants: AJINOMOTO CO., INC. [JP/JP]; 15-1, Kyobashi 1-chome, Chuo-ku, Tokyo, 1048315 (JP) (For All Designated States Except US).
KOZLOV, Yury, Ivanovich [RU/RU]; (RU) (For US Only).
CHINEN, Akito [JP/JP]; (JP) (For US Only).
IZUI, Hiroshi [JP/JP]; (JP) (For US Only).
HARA, Yoshihiko [JP/JP]; (JP) (For US Only).
YASUEDA, Hisashi [JP/JP]; (JP) (For US Only).
RYBAK, Konstantin, Vyacheslavovich [RU/RU]; (RU) (For US Only).
SLIVINSKAYA, Ekaterina, Aleksandrovna [RU/RU]; (RU) (For US Only).
KATASHKINA, Joanna, Yosifovna [RU/RU]; (RU) (For US Only)
Inventors: KOZLOV, Yury, Ivanovich; (RU).
CHINEN, Akito; (JP).
IZUI, Hiroshi; (JP).
HARA, Yoshihiko; (JP).
YASUEDA, Hisashi; (JP).
RYBAK, Konstantin, Vyacheslavovich; (RU).
SLIVINSKAYA, Ekaterina, Aleksandrovna; (RU).
KATASHKINA, Joanna, Yosifovna; (RU)
Agent: KAWAGUCHI, Yoshiyuki; Acropolis 21 Building 6th Floor, 4-10, Higashi Nihonbashi 3-chome, Chuo-ku, Tokyo 1030004 (JP)
Priority Data:
2004124226 10.08.2004 RU
60/644,562 19.01.2005 US
Title (EN) THE USE OF PHOSPHOKETOLASE FOR PRODUCING USEFUL METABOLITES
(FR) UTILISATION DE PHOSPHOCETOLASE POUR PRODUIRE DES METABOLITES UTILES
Abstract: front page image
(EN)The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.
(FR)L'invention concerne une bactérie permettant de produire un métabolite utile dérivé d'un acétyl-coenzyme A, notamment de l'acide L-glutamique, de la L-glutamine, de la L-proline, de la L-arginine, de la L-leucine, de la L-cystéine, du succinate et du polyhydroxybutyrate. Cette bactérie est modifiée de sorte à accroître les activités de la D-xylulose-5-phosphate phosphocétolase et/ou de la fructose-6-phosphate phosphocétolase. L'invention concerne également une méthode pour produire le métabolite utile susmentionné au moyen de la bactérie de l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)