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1. (WO2006016548) NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2006/016548 International Application No.: PCT/JP2005/014505
Publication Date: 16.02.2006 International Filing Date: 08.08.2005
IPC:
A61K 31/465 (2006.01) ,A61K 31/47 (2006.01) ,A61K 31/4709 (2006.01) ,A61P 33/06 (2006.01) ,C07D 213/82 (2006.01) ,C07D 405/12 (2006.01) ,C07D 409/12 (2006.01)
Applicants: NAKAMOTO, Kazutaka[JP/JP]; JP (UsOnly)
MATSUKURA, Masayuki[JP/JP]; JP (UsOnly)
TANAKA, Keigo[JP/JP]; JP (UsOnly)
INOUE, Satoshi[JP/JP]; JP (UsOnly)
TSUKADA, Itaru[JP/JP]; JP (UsOnly)
HANEDA, Toru[JP/JP]; JP (UsOnly)
UEDA, Norihiro[JP/JP]; JP (UsOnly)
ABE, Shinya[JP/JP]; JP (UsOnly)
SAGANE, Koji[JP/JP]; JP (UsOnly)
EISAI R & D MANAGEMENT CO., LTD.[JP/JP]; 6-10, Koishikawa 4-chome, Bunkyo-ku Tokyo 1128088, JP (AllExceptUS)
Inventors: NAKAMOTO, Kazutaka; JP
MATSUKURA, Masayuki; JP
TANAKA, Keigo; JP
INOUE, Satoshi; JP
TSUKADA, Itaru; JP
HANEDA, Toru; JP
UEDA, Norihiro; JP
ABE, Shinya; JP
SAGANE, Koji; JP
Agent: INABA, Yoshiyuki; TMI ASSOCIATES, 23rd Floor Roppongi Hills Mori Tower 6-10-1, Roppongi Minato-ku, Tokyo 106-6123, JP
Priority Data:
2004-23261709.08.2004JP
2005-08276022.03.2005JP
PCT/JP2004/01406327.09.2004JP
Title (EN) NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND
(FR) AGENT ANTIPALUDIQUE INNOVANT CONTENANT UN COMPOSE HÉTÉROCYCLIQUE
(JA) ヘテロ環化合物を含有する新規な抗マラリア剤
Abstract: front page image
(EN) An antimalaria agent containing a compound represented by the formula (I-a) (wherein A1 means optionally substituted 3-pyridyl, optionally substituted 6-quinolyl, etc.; X1 means a group represented by the formula -C(=O)-NH-, etc.; and E means furyl, thienyl, or phenyl; provided that A1 may have one to three substituents and E has one or two substituents), a salt of the compound, or a hydrate of either.
(FR) Agent antipaludique contenant un composé représenté par la formule (I-a) (dans laquelle A1 représente un 3-pyridyle éventuellement substitué, un 6-quinolyle éventuellement substitué, etc. ; X1 représente un groupe représenté par la formule -C(=O)-NH-, etc. ; et E représente un furyle, thiényle, ou phényle ; à condition que A1 puisse avoir de un à trois substituants et E ait un ou deux substituants), un sel du composé, ou un hydrate de l’un ou l’autre.
(JA)  式 〔式中、Aは、置換基を有していてもよい3-ピリジル基、置換基を有していてもよい6-キノリル基等を意味する;Xは、式-C(=O)-NH-で表される基等を意味する;Eは、フリル基、チエニル基またはフェニル基を意味する; ただし、Aは、置換基を1ないし3個有していてもよく、Eは、置換基を1または2個有する。〕で表される化合物もしくはその塩またはそれらの水和物を含有する抗マラリア剤。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)