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1. (WO2006014779) METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY DISORDERS OF THE GASTROINTESTINAL TRACT
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2006/014779 International Application No.: PCT/US2005/025914
Publication Date: 09.02.2006 International Filing Date: 21.07.2005
IPC:
A61K 31/045 (2006.01) ,A61P 1/00 (2006.01) ,A61P 1/04 (2006.01) ,A61P 35/00 (2006.01)
Applicants: BERLIN, Roger[US/US]; US (UsOnly)
WYETH[US/US]; Five Giralda Farms Madison, New Jersey 07940, US (AllExceptUS)
Inventors: BERLIN, Roger; US
Agent: FLYNN, Steven, H.; Wyeth Patent Law Department Five Giralda Farms Madison, New Jersey 07940 , US
Priority Data:
10/898,89626.07.2004US
Title (EN) METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY DISORDERS OF THE GASTROINTESTINAL TRACT
(FR) METHODES ET COMPOSITIONS DE TRAITEMENT DE TROUBLES INFLAMMATOIRES DU TRACTUS GASTRO-INTESTINAL
Abstract:
(EN) The present invention provides compositions and methods for treating or preventing the development of inflammatory disorder of the gastrointestinal tract in a subject, comprising administering to a subject therapeutically effective amount of a biologically active mixture of high purity, high molecular weight straight chain primary aliphatic alcohols (referred to collectively herein as policosanol). Inflammatory conditions that can be addressed by the compositions and methods of this invention include colorectal cancer, neoplasm of the colon, neoplasm of the rectum, ulcerative colitis, adenomatous polyps, familial polyposis, stomach cancer, and combinations thereof.
(FR) La présente invention concerne des compositions et des méthodes de traitement ou de prévention du développement de troubles inflammatoires du tractus gastro-intestinal chez un sujet, comprenant l’administration à un sujet d’une quantité thérapeutiquement efficace d’un mélange biologiquement actif d’alcools aliphatiques primaires à chaîne linéaire, de haut poids moléculaire et de haute pureté (désignés collectivement dans ce qui suit par « policosanol »). Les conditions inflammatoires pouvant être ciblées par les compositions et les méthodes de la présente invention comportent le cancer colorectal, les tumeurs du côlon, les tumeurs du rectum, la rectocolite ulcérative, les polypes adénomateux, la polypose familiale, le cancer de l’estomac, et des associations de ceux-ci.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)