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1. (WO2006014642) METHOD OF PRODUCING AUTOLOGOUS EMBRYONIC STEM CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/014642    International Application No.:    PCT/US2005/025580
Publication Date: 09.02.2006 International Filing Date: 19.07.2005
IPC:
C12N 5/0735 (2010.01), C12N 5/10 (2006.01), A01K 67/027 (2006.01), C12N 15/873 (2010.01)
Applicants: FIVE PRIME THERAPEUTICS, INC. [US/US]; 1650 Owens Street, Suite 200, San Francisco, CA 94158-2261 (US) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
WILLIAMS, Lewis, T. [US/US]; (US) (For US Only).
ZHANG, Hongbing [CN/US]; (US) (For US Only).
KOTHAKOTA, Srinivas [IN/US]; (US) (For US Only).
PIERCE, Kristen [US/US]; (US) (For US Only).
BEAURANG, Pierre, Alvaro [BE/US]; (US) (For US Only).
CHU, Keting [US/US]; (US) (For US Only)
Inventors: WILLIAMS, Lewis, T.; (US).
ZHANG, Hongbing; (US).
KOTHAKOTA, Srinivas; (US).
PIERCE, Kristen; (US).
BEAURANG, Pierre, Alvaro; (US).
CHU, Keting; (US)
Agent: GARRETT, Arthur, S.; Finnegan, Henderson, Farrabow, Garrett & Dunner LLP, 901 New York Avenue, NW, Washington, DC 20001 (US)
Priority Data:
60/590,797 22.07.2004 US
Title (EN) METHOD OF PRODUCING AUTOLOGOUS EMBRYONIC STEM CELLS
(FR) PROCEDE DE PRODUCTION DE CELLULES SOUCHES EMBRYONNAIRES AUTOLOGUES
Abstract: front page image
(EN)Aspects of the present invention relate to compositions and methods of reprogramming a somatic cell to give rise to an autologous embryonic stem cell. These methods involve providing a somatic cell of a donor subject, introducing the somatic cell into an embryo of a recipient subject to produce a chimeric embryo, allowing the chimeric embryo to develop further wherein the somatic cell will reprogram, and then selecting an autologous embryonic stem cell that has developed from the somatic cell. The methods and composition of producing pluripotent embryonic stem cells from a donor’s own somatic cells invite the possibility of a number of therapeutic applications, including organ transplant and treatment of autoimmune diseases, cancer, and degenerative disorders such as diabetes, Alzheimer’s, and Parkinson’s.
(FR)La présente invention concerne des compositions et des procédés pour la reprogammation d'une cellule somatique destinée à générer une cellule souche embryonnaire autologue. Lesdits procédés consistent à se munir d'une cellule somatique d'un sujet donneur, à introduire cette cellule somatique dans l'embryon d'un sujet receveur pour produire un embryon chimère, à faire développer cet embryon chimère de façon que la cellule somatique soit reprogrammée, et à sélectionner une cellule souche embryonnaire autologue qui s'est développée à partir de la cellule somatique. Ces procédés et compositions pour la production de cellules souches embryonnaires pluripotentes à partir de cellules somatiques du donneur permettent toute une variété d'applications thérapeutiques, y compris la transplantation d'organes et le traitement de maladies auto-immunes, du cancer et de maladies dégénératives telles que le diabète, la maladie d'Alzheimer et la maladie de Parkinson.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)