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1. (WO2006013209) COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2006/013209 International Application No.: PCT/EP2005/053778
Publication Date: 09.02.2006 International Filing Date: 02.08.2005
IPC:
A61K 31/165 (2006.01) ,A61K 31/166 (2006.01) ,A61K 31/167 (2006.01) ,A61K 31/18 (2006.01) ,A61K 31/198 (2006.01) ,A61K 31/401 (2006.01) ,A61K 31/404 (2006.01) ,A61K 31/47 (2006.01) ,A61K 31/4709 (2006.01) ,C07C 259/00 (2006.01) ,A61K 31/16 (2006.01) ,A61K 31/405 (2006.01)
Applicants: MARTI CLAUZEL, Luc[FR/ES]; ES (UsOnly)
GARCIA VICENTE, Silvia[ES/ES]; ES (UsOnly)
YRAOLA FONT, Francesc[ES/ES]; ES (UsOnly)
ROYO EXPOSITO, Miriam[ES/ES]; ES (UsOnly)
GENMEDICA THERAPEUTICS SL[ES/ES]; Zamora 75 E-08018 Barcelona, ES (AllExceptUS)
Inventors: MARTI CLAUZEL, Luc; ES
GARCIA VICENTE, Silvia; ES
YRAOLA FONT, Francesc; ES
ROYO EXPOSITO, Miriam; ES
Agent: SMAGGASGALE, Gillian Helen; W. P. Thompson & Co. 55 Drury Lane London WC2B 5SQ, GB
Priority Data:
60/598,01002.08.2004US
Title (EN) COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF
(FR) COMPOSES INHIBANT LES AMINE OXYDASES CONTENANT DU CUIVRE, ET UTILISATIONS CORRESPONDANTES
Abstract:
(EN) This invention is directed to inhibitors of copper-containing amine oxidases (E.C.1.4.3.6) including semicarbazide-sensitive amine oxidase (SSAO; also known as vascular adhesion protein- 1, VAP-I), and their therapeutic use in inflammatory diseases, diabetes and its associated complications, atherosclerosis, neurodegenerative diseases, obesity, hypertension and cancer.
(FR) L'invention concerne des inhibiteurs d'amine oxydases contenant du cuivre (E.C.1.4.3.6) y compris l'amine oxydase sensible au semi-carbazide (SSAO; que l'on appelle aussi protéine 1 d'adhésion vasculaire, VAP-I), et leur utilisation thérapeutique pour les maladies inflammatoires, le diabète et ses complications associées, l'athérosclérose, les maladies neurodégénératives, l'obésité, l'hypertension et le cancer.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)