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1. (WO2006013107) IL-17 ANTAGONISTIC ANTIBODIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/013107    International Application No.:    PCT/EP2005/008470
Publication Date: 09.02.2006 International Filing Date: 04.08.2005
IPC:
A61K 39/395 (2006.01), A61P 29/00 (2006.01), C07K 16/24 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35, CH-4056 Basel (CH) (AE, AG, AL, AM, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
NOVARTIS PHARMA GMBH [AT/AT]; Brunner Strasse 59, A-1230 Vienna (AT) (AT only).
DI PADOVA, Franco, E. [IT/CH]; (CH) (For US Only).
GRAM, Hermann [DE/DE]; (DE) (For US Only).
HOFSTETTER, Hans [CH/CH]; (CH) (For US Only).
JESCHKE, Margit [DE/CH]; (CH) (For US Only).
RONDEAU, Jean-Michel [FR/FR]; (FR) (For US Only).
VAN DEN BERG, Wim [NL/NL]; (NL) (For US Only)
Inventors: DI PADOVA, Franco, E.; (CH).
GRAM, Hermann; (DE).
HOFSTETTER, Hans; (CH).
JESCHKE, Margit; (CH).
RONDEAU, Jean-Michel; (FR).
VAN DEN BERG, Wim; (NL)
Agent: HILLEBRAND, Dirk; Novartis AG, Corporate Intellectual Property, CH-4002 Basel (CH)
Priority Data:
0417487.6 05.08.2004 GB
Title (EN) IL-17 ANTAGONISTIC ANTIBODIES
(FR) ANTICORPS ANTAGONISTES DE IL-17
Abstract: front page image
(EN)An IL-17 binding molecule, in particular an antibody to human IL-17, more preferably a human antibody to IL-17 is provided, wherein the hypervariable regions of the heavy and light chains have amino acid sequences as defined, for use in the treatment of an IL-17 mediated disease or disorder, e.g. rheumatoid arthritis.
(FR)Cette invention concerne une molécule de liaison de l'IL-17, en particulier un anticorps de l'IL-17 humain, mieux encore un anticorps humain de l'IL-17, dont les régions hypervariables des chaînes lourdes et légères présentent des séquences d'acides aminés comme indiqué dans le descriptif, et qui dont l'utilisation convient pour le traitement des maladies ou des troubles induits par IL-17 tels que la polyarthrite rhumatoïde..
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)